DisGeNET - a database of gene-disease associations

KCNQ1, potassium voltage-gated channel subfamily Q member 1, 3784

N. diseases: 281; N. variants: 380

Disease: Diabetes Mellitus, Non-Insulin-Dependent ×

Variant: rs163177 ×

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Disease

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs163177

Entrez Id:	3784
Gene Symbol:	KCNQ1

KCNQ1

CUI:	C0011860
Disease:

Diabetes Mellitus, Non-Insulin-Dependent

0.810

GeneticVariation

BEFREE

A total of 3 SNPs [rs9465871 (CDKAL1), rs10761745 (JMJD1C), and rs163177 (KCNQ1)] were selected as candidate SNPs related to T2D.

28406950

2017

dbSNP:

rs163177

Entrez Id:	3784
Gene Symbol:	KCNQ1

KCNQ1

CUI:	C0011860
Disease:

Diabetes Mellitus, Non-Insulin-Dependent

0.810

GeneticVariation

GWASCAT

Among them, rs10761745 (JMJD1C) and rs163177 (KCNQ1) were prospectively associated with T2D.

28406950

2017

dbSNP:

rs163177

Entrez Id:	3784
Gene Symbol:	KCNQ1

KCNQ1

CUI:	C0011860
Disease:

Diabetes Mellitus, Non-Insulin-Dependent

0.810

GeneticVariation

GWASDB

A genome-wide association study identifies susceptibility variants for type 2 diabetes in Han Chinese.

20174558

2010