Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2237892
rs2237892
Entrez Id: 3784
Gene Symbol: KCNQ1
KCNQ1
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent
0.900 GeneticVariation BEFREE Haploview analysis showed that the ACC (rs151290, rs2237892 and rs2237895) haplotype is the most significant risk allele combination for CVD, while CCA is the most significant risk haplotype for co-morbidity with T2D. 28863213 2019
dbSNP: rs2237895
rs2237895
Entrez Id: 3784
Gene Symbol: KCNQ1
KCNQ1
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent
0.900 GeneticVariation BEFREE KCNQ1 polymorphism at SNPs rs151290 and rs2237895 is strongly associated with CVD in this population, but presented no association with T2D. 28863213 2019
dbSNP: rs2237895
rs2237895
Entrez Id: 3784
Gene Symbol: KCNQ1
KCNQ1
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent
0.900 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs2237892
rs2237892
Entrez Id: 3784
Gene Symbol: KCNQ1
KCNQ1
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent
T 0.900 GeneticVariation GWASCAT Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes. 30054458 2018
dbSNP: rs2237892
rs2237892
Entrez Id: 3784
Gene Symbol: KCNQ1
KCNQ1
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent
0.900 GeneticVariation BEFREE The results of the present pilot study suggest for the first time that the KCNQ1 rs2237892 may constitute a shared genetic risk factor for RA and CP, but not for T2DM and CP in Japanese adults. 29520783 2018
dbSNP: rs2237892
rs2237892
Entrez Id: 3784
Gene Symbol: KCNQ1
KCNQ1
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent
T 0.900 GeneticVariation GWASCAT Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease. 28869590 2017
dbSNP: rs2237892
rs2237892
Entrez Id: 3784
Gene Symbol: KCNQ1
KCNQ1
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent
0.900 GeneticVariation BEFREE The main anthropometric and biochemical parameters did not correlate with the rs2237892 or rs2237895 SNPs in the T2DM group (P > 0.05). 27323013 2016
dbSNP: rs2237895
rs2237895
Entrez Id: 3784
Gene Symbol: KCNQ1
KCNQ1
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent
0.900 GeneticVariation BEFREE The main anthropometric and biochemical parameters did not correlate with the rs2237892 or rs2237895 SNPs in the T2DM group (P > 0.05). 27323013 2016
dbSNP: rs2237895
rs2237895
Entrez Id: 3784
Gene Symbol: KCNQ1
KCNQ1
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent
0.900 GeneticVariation BEFREE Three loci showed nominal POE, including the previously reported variants in KCNQ1, for type 2 diabetes in families from Botnia (rs2237895: p POE  = 0.037), which can be considered positive controls. 27155871 2016
dbSNP: rs2237892
rs2237892
Entrez Id: 3784
Gene Symbol: KCNQ1
KCNQ1
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent
0.900 GeneticVariation BEFREE The C allele of rs2237892 variant contributed to susceptibility to T2DM (odds ratio [OR], 1.45; 95% confidence interval [CI], 1.20-1.75). 26678516 2015
dbSNP: rs2237892
rs2237892
Entrez Id: 3784
Gene Symbol: KCNQ1
KCNQ1
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent
0.900 GeneticVariation BEFREE Rs5215, rs10811661, and rs2237892 were in significant association with T2DM, and hazard ratios per risk allele score increase were 1.11 (95% confidence intervals: 1.06-1.17), 1.09 (1.01-1.05), 1.04 (1.02-1.07) with GPS-3, GPS-18, GPS-36, respectively. 26240488 2015
dbSNP: rs2237895
rs2237895
Entrez Id: 3784
Gene Symbol: KCNQ1
KCNQ1
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent
0.900 GeneticVariation BEFREE Results showed that the T2D risk alleles of rs243021 located near BCL11A, rs10830963 in MTNR1B, and rs2237895 in KCNQ1 were related to a lower risk for abdominal obesity in T2D patients (rs243021: 0.92 (0.84, 1.00), P = 4.42 × 10-2; rs10830963: 0.92 (0.85, 1.00), P = 4.07 × 10-2; rs2237895: 0.89 (0.82, 0.98), P = 1.29 × 10-2). 26599349 2015
dbSNP: rs2237892
rs2237892
Entrez Id: 3784
Gene Symbol: KCNQ1
KCNQ1
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent
C 0.900 GeneticVariation GWASDB Genome-wide association study identifies three novel loci for type 2 diabetes. 23945395 2014
dbSNP: rs2237892
rs2237892
Entrez Id: 3784
Gene Symbol: KCNQ1
KCNQ1
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent
0.900 GeneticVariation BEFREE KCNQ1 rs2237892 C→T gene polymorphism and type 2 diabetes mellitus in the Asian population: a meta-analysis of 15,736 patients. 24373634 2014
dbSNP: rs2237892
rs2237892
Entrez Id: 3784
Gene Symbol: KCNQ1
KCNQ1
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent
C 0.900 GeneticVariation GWASCAT Genome-wide association study identifies three novel loci for type 2 diabetes. 23945395 2014
dbSNP: rs2237895
rs2237895
Entrez Id: 3784
Gene Symbol: KCNQ1
KCNQ1
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent
0.900 GeneticVariation BEFREE Variants in the KCNQ1 (rs2237895, p = 0.0012), HHEX (rs1111875, p = 0.0024 in Finns) and MTNR1B (rs10830963, p = 0.0039) loci showed the strongest association in patients with low GADA, supporting the hypothesis that the disease in these patients is more like type 2 diabetes. 24906951 2014
dbSNP: rs2237892
rs2237892
Entrez Id: 3784
Gene Symbol: KCNQ1
KCNQ1
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent
C 0.900 GeneticVariation GWASCAT A genome-wide association study identifies GRK5 and RASGRP1 as type 2 diabetes loci in Chinese Hans. 22961080 2013
dbSNP: rs2237892
rs2237892
Entrez Id: 3784
Gene Symbol: KCNQ1
KCNQ1
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent
0.900 GeneticVariation BEFREE Overall, significantly elevated T2D risk was associated with rs2237892, rs2237895, rs2237897, rs2283228, and rs231362 risk allele when all studies were pooled into the meta-analysis. 23271129 2013
dbSNP: rs2237892
rs2237892
Entrez Id: 3784
Gene Symbol: KCNQ1
KCNQ1
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent
0.900 GeneticVariation BEFREE COL8A1 rs792837 (P=2.9 × 10(-9)), KCNQ1 rs2237892 (P=1.8 × 10(-18)) and rs2237895 (P=0.002), ALX4 rs729287 (Pc=7.5 × 10(-5)), and HNF1 rs4430796 (P=0.003) were significantly associated with T2DM, with similar effect sizes to those of Europeans. 24145053 2013
dbSNP: rs2237892
rs2237892
Entrez Id: 3784
Gene Symbol: KCNQ1
KCNQ1
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent
0.900 GeneticVariation BEFREE We aimed to evaluate the effect of four common variants (rs2237892, rs2283228, rs2237895, and rs2237897) in KCNQ1 on susceptibility of type 2 diabetes (T2D) by performing a case-control study as well as a comprehensive meta-analysis. 23786590 2013
dbSNP: rs2237892
rs2237892
Entrez Id: 3784
Gene Symbol: KCNQ1
KCNQ1
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent
C 0.900 GeneticVariation GWASDB A genome-wide association study identifies GRK5 and RASGRP1 as type 2 diabetes loci in Chinese Hans. 22961080 2013
dbSNP: rs2237895
rs2237895
Entrez Id: 3784
Gene Symbol: KCNQ1
KCNQ1
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent
0.900 GeneticVariation BEFREE We aimed to evaluate the effect of four common variants (rs2237892, rs2283228, rs2237895, and rs2237897) in KCNQ1 on susceptibility of type 2 diabetes (T2D) by performing a case-control study as well as a comprehensive meta-analysis. 23786590 2013
dbSNP: rs2237895
rs2237895
Entrez Id: 3784
Gene Symbol: KCNQ1
KCNQ1
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent
0.900 GeneticVariation BEFREE COL8A1 rs792837 (P=2.9 × 10(-9)), KCNQ1 rs2237892 (P=1.8 × 10(-18)) and rs2237895 (P=0.002), ALX4 rs729287 (Pc=7.5 × 10(-5)), and HNF1 rs4430796 (P=0.003) were significantly associated with T2DM, with similar effect sizes to those of Europeans. 24145053 2013
dbSNP: rs2237895
rs2237895
Entrez Id: 3784
Gene Symbol: KCNQ1
KCNQ1
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent
0.900 GeneticVariation BEFREE Genotype at the type 2 diabetes risk variant rs2237895 influenced methylation levels of regulatory sequence in fetal pancreas but without demonstrable effects on gene expression. 23139357 2013
dbSNP: rs2237892
rs2237892
Entrez Id: 3784
Gene Symbol: KCNQ1
KCNQ1
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent
0.900 GeneticVariation BEFREE Association to type 2 diabetes was found for rs13266634 (SLC30A8), rs7923837 (HHEX), rs10811661 (CDKN2A/2B), rs4402960 (IGF2BP2), rs12779790 (CDC123/CAMK1D), and rs2237892 (KCNQ1). 22923468 2012