rs121913517
×
Entrez Id:
3815
Gene Symbol:
KIT
KIT
melanoma
G
0.700
CausalMutation
CLINVAR
The GIST of targeted therapy for malignant melanoma.
24531699
2014
rs121913517
×
Entrez Id:
3815
Gene Symbol:
KIT
KIT
melanoma
A
0.700
CausalMutation
CLINVAR
Prospective enterprise-level molecular genotyping of a cohort of cancer patients.
25157968
2014
rs121913517
×
Entrez Id:
3815
Gene Symbol:
KIT
KIT
melanoma
C
0.700
GeneticVariation
CLINVAR
A meta-analysis of somatic mutations from next generation sequencing of 241 melanomas: a road map for the study of genes with potential clinical relevance.
24755198
2014
rs121913517
×
Entrez Id:
3815
Gene Symbol:
KIT
KIT
melanoma
C
0.700
GeneticVariation
CLINVAR
Prospective enterprise-level molecular genotyping of a cohort of cancer patients.
25157968
2014
rs121913517
×
Entrez Id:
3815
Gene Symbol:
KIT
KIT
melanoma
G
0.700
CausalMutation
CLINVAR
Transcriptome sequencing of melanocytic nevi and melanomas from Grm1 transgenic mice to determine melanoma driver mutations.
24661573
2014
rs121913517
×
Entrez Id:
3815
Gene Symbol:
KIT
KIT
melanoma
A
0.700
CausalMutation
CLINVAR
Phase II, open-label, single-arm trial of imatinib mesylate in patients with metastatic melanoma harboring c-Kit mutation or amplification.
21690468
2011
rs121913517
×
Entrez Id:
3815
Gene Symbol:
KIT
KIT
melanoma
A
0.700
CausalMutation
CLINVAR
KIT as a therapeutic target in metastatic melanoma.
21642685
2011
rs121913517
×
Entrez Id:
3815
Gene Symbol:
KIT
KIT
melanoma
C
0.700
GeneticVariation
CLINVAR
V559A and N822I double KIT mutant melanoma with predictable response to imatinib?
21159146
2011
rs121913517
×
Entrez Id:
3815
Gene Symbol:
KIT
KIT
melanoma
A
0.700
CausalMutation
CLINVAR
Response to imatinib mesylate depends on the presence of the V559A-mutated KIT oncogene.
19812602
2010
rs121913517
×
Entrez Id:
3815
Gene Symbol:
KIT
KIT
melanoma
C
0.700
GeneticVariation
CLINVAR
Response to imatinib mesylate depends on the presence of the V559A-mutated KIT oncogene.
19812602
2010
rs121913517
×
Entrez Id:
3815
Gene Symbol:
KIT
KIT
melanoma
A
0.700
CausalMutation
CLINVAR
Activity of dasatinib against L576P KIT mutant melanoma: molecular, cellular, and clinical correlates.
19671763
2009
rs121913517
×
Entrez Id:
3815
Gene Symbol:
KIT
KIT
melanoma
A
0.700
CausalMutation
CLINVAR
Complete response of stage IV anal mucosal melanoma expressing KIT Val560Asp to the multikinase inhibitor sorafenib.
18936790
2008
rs121913517
×
Entrez Id:
3815
Gene Symbol:
KIT
KIT
melanoma
C
0.700
GeneticVariation
CLINVAR
KIT gene mutations and copy number in melanoma subtypes.
18980976
2008
rs121913517
×
Entrez Id:
3815
Gene Symbol:
KIT
KIT
melanoma
A
0.700
CausalMutation
CLINVAR
KIT gene mutations and copy number in melanoma subtypes.
18980976
2008
rs121913517
×
Entrez Id:
3815
Gene Symbol:
KIT
KIT
melanoma
A
0.700
CausalMutation
CLINVAR
L576P KIT mutation in anal melanomas correlates with KIT protein expression and is sensitive to specific kinase inhibition.
17372901
2007
rs121913517
×
Entrez Id:
3815
Gene Symbol:
KIT
KIT
melanoma
C
0.700
GeneticVariation
CLINVAR
L576P KIT mutation in anal melanomas correlates with KIT protein expression and is sensitive to specific kinase inhibition.
17372901
2007
rs121913517
×
Entrez Id:
3815
Gene Symbol:
KIT
KIT
melanoma
C
0.700
GeneticVariation
CLINVAR
Somatic activation of KIT in distinct subtypes of melanoma.
16908931
2006
rs121913517
×
Entrez Id:
3815
Gene Symbol:
KIT
KIT
melanoma
A
0.700
CausalMutation
CLINVAR
Somatic activation of KIT in distinct subtypes of melanoma.
16908931
2006
rs121913517
×
Entrez Id:
3815
Gene Symbol:
KIT
KIT
melanoma
A
0.700
CausalMutation
CLINVAR
Activation mutations of human c-KIT resistant to imatinib mesylate are sensitive to the tyrosine kinase inhibitor PKC412.
15790786
2005
rs121913517
×
Entrez Id:
3815
Gene Symbol:
KIT
KIT
melanoma
A
0.700
CausalMutation
CLINVAR
Inhibition of drug-resistant mutants of ABL, KIT, and EGF receptor kinases.
16046538
2005
rs121913517
×
Entrez Id:
3815
Gene Symbol:
KIT
KIT
melanoma
C
0.700
GeneticVariation
CLINVAR
Activation mutations of human c-KIT resistant to imatinib mesylate are sensitive to the tyrosine kinase inhibitor PKC412.
15790786
2005
rs121913517
×
Entrez Id:
3815
Gene Symbol:
KIT
KIT
melanoma
A
0.700
CausalMutation
CLINVAR
Gain-of-function mutation at the extracellular domain of KIT in gastrointestinal stromal tumours.
11276010
2001
rs121913517
×
Entrez Id:
3815
Gene Symbol:
KIT
KIT
melanoma
C
0.700
GeneticVariation
CLINVAR
Gain-of-function mutation at the extracellular domain of KIT in gastrointestinal stromal tumours.
11276010
2001
rs121913517
×
Entrez Id:
3815
Gene Symbol:
KIT
KIT
melanoma
A
0.700
CausalMutation
CLINVAR
Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors.
9438854
1998
rs121913517
×
Entrez Id:
3815
Gene Symbol:
KIT
KIT
melanoma
C
0.700
GeneticVariation
CLINVAR
Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors.
9438854
1998