LEPR, leptin receptor, 3953

N. diseases: 416; N. variants: 57
Disease: Squamous cell carcinoma ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1256046734
rs1256046734
Entrez Id: 3953
Gene Symbol: LEPR
LEPR
CUI: C0007137
Disease:
Squamous cell carcinoma 		0.010 GeneticVariation BEFREE The incidence of leptin gene G2548A homozygous mutant AA polymorphism was significantly increased in the OSCC patients (p = 0.002, odds ratio (OR) = 2.4, 95 % confidence interval (CI) = 1.37-4.22) when compared with controls, and leptin receptor A668G homozygous mutant GG polymorphism was significantly high in the OSCC patients as compared to controls (p = 0.000, OR = 3.8, 95 % CI = 1.98-7.62). 25809704 2015