LMNA, lamin A/C, 4000

N. diseases: 824; N. variants: 285
Disease: Atrial Fibrillation ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs58672172
rs58672172
Entrez Id: 4000
Gene Symbol: LMNA
LMNA
CUI: C0004238
Disease:
Atrial Fibrillation 		0.010 GeneticVariation BEFREE In conclusion, our results indicate that lamin A/C mutation p.Arg399Cys weakens the interaction between nuclear lamina (lamin A/C) and the nuclear pore complex (NUP155), leading to the development of AF. 30488537 2019