LPL, lipoprotein lipase, 4023

N. diseases: 290; N. variants: 116
Disease: Metabolic Syndrome X ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs328
rs328
Entrez Id: 4023
Gene Symbol: LPL
LPL
CUI: C0524620
Disease:
Metabolic Syndrome X 		0.020 GeneticVariation BEFREE Diets high in carbohydrate may not be appropriate for rs328 G carriers with the metabolic syndrome. 26420199 2015
dbSNP: rs328
rs328
Entrez Id: 4023
Gene Symbol: LPL
LPL
CUI: C0524620
Disease:
Metabolic Syndrome X 		0.020 GeneticVariation BEFREE We found an association with elevated glucose levels (odds ratio (OR) = 2.9; p = 0.013) in carrying the AA genotype of rs1884051 in the ESR1 gene compared with the GG genotype, and the CC genotype of rs328 in the LPL gene was associated with MetS compared to the CG or GG genotype (OR = 2.8; p = 0.04). 26370976 2015