|
rs353291
|
MIR145;CARMN
|
Arteriosclerosis
|
|
0.010 |
GeneticVariation |
BEFREE |
These data suggest that the rs353291 C allele may increase susceptibility to atherosclerosis.
|
31585905 |
2020 |
|
rs353291
|
MIR145;CARMN
|
Atherosclerosis
|
|
0.010 |
GeneticVariation |
BEFREE |
These data suggest that the rs353291 C allele may increase susceptibility to atherosclerosis.
|
31585905 |
2020 |
|
rs190323149
|
MIR145;CARMN
|
Ischemic stroke
|
|
0.010 |
GeneticVariation |
BEFREE |
This study evaluated the associations of hsa-mir-608 C/G rs4919510, hsa-mir-499 A/G rs3746444, and hsa-mir-145 C/T rs190323149 polymorphisms in precursor miRNAs with the risk of IS.
|
30229913 |
2019 |
|
rs353291
|
MIR145;CARMN
|
Septicemia
|
|
0.010 |
GeneticVariation |
BEFREE |
The T allele of the miR-21 SNP rs13137 and the T allele of the miR-145 SNP rs353291 (OR = 0.685, 95% CI = 0.566-0.820, P < .001) were found to be a protective factor for sepsis (OR = 0.755, 95% CI = 0.632-0.896, P < .001).
|
31415369 |
2019 |
|
rs353291
|
MIR145;CARMN
|
Sepsis
|
|
0.010 |
GeneticVariation |
BEFREE |
The T allele of the miR-21 SNP rs13137 and the T allele of the miR-145 SNP rs353291 (OR = 0.685, 95% CI = 0.566-0.820, P < .001) were found to be a protective factor for sepsis (OR = 0.755, 95% CI = 0.632-0.896, P < .001).
|
31415369 |
2019 |
|
rs41291957
|
MIR143;MIR145;CARMN
|
Lymphoma, Non-Hodgkin
|
|
0.010 |
GeneticVariation |
BEFREE |
We identified three SNPs in MIR143 that are to be significantly associated with reduced risk of NHL: rs3733846 (odds ratio (OR) [95% confidence interval (CI)] = 0.54 [0.33 ⁻ 0.86], p = 0.010), rs41291957 (OR [95% CI] = 0.61 [0.39 ⁻ 0.94], p = 0.024), and rs17723799 (OR [95% CI] = 0.43 [0.26 ⁻ 0.71], p = 0.0009).
|
30818878 |
2019 |
|
rs74693964
|
MIR145;CARMN
|
Non-Small Cell Lung Carcinoma
|
|
0.010 |
GeneticVariation |
BEFREE |
In the current study, we investigated the associations of single nucleotide polymorphisms (SNPs) in miRNAs (rs11134527 in <i>pri-miR-218-2</i>, rs74693964 in <i>pri-miR-145</i>, rs6062251 in <i>pri-miR-133a-2</i>, and rs4705343 in <i>pri-miR-143</i>) with nonsmall cell lung cancer (NSCLC) in a Han population from Yunnan Province, Southwest China using a binary logistic regression analysis.
|
29692628 |
2018 |
|
rs41291957
|
MIR143;MIR145;CARMN
|
Colorectal Carcinoma
|
|
0.010 |
GeneticVariation |
BEFREE |
However, the association of six polymorphisms (miR-608 rs4919510, miR-499a rs3746444, miR-146a rs2910164, pre-miR-143 rs41291957, pre-miR-124-1 rs531564 and pre-miR-26a-1 rs7372209) with colorectal cancer (CRC) risk, therapeutic response and survival remains unclear.
|
27713147 |
2016 |
|
rs353291
|
MIR145;CARMN
|
Malignant neoplasm of breast
|
|
0.010 |
GeneticVariation |
BEFREE |
However, we were able to show association between rs353291 (located in MIR145) and the risk of developing breast cancer in two independent case control cohorts (p = 0.041 and p = 0.023).
|
26577090 |
2015 |
|
rs353291
|
MIR145;CARMN
|
Breast Carcinoma
|
|
0.010 |
GeneticVariation |
BEFREE |
However, we were able to show association between rs353291 (located in MIR145) and the risk of developing breast cancer in two independent case control cohorts (p = 0.041 and p = 0.023).
|
26577090 |
2015 |
|
rs41291957
|
MIR143;MIR145;CARMN
|
Carcinogenesis
|
|
0.010 |
GeneticVariation |
BEFREE |
The rs41291957 variant located in the pri-miR-143 sequence is associated with colorectal carcinogenesis.
|
24752771 |
2014 |
|
rs41291957
|
MIR143;MIR145;CARMN
|
Coronary heart disease
|
|
0.010 |
GeneticVariation |
BEFREE |
Logistic regression analyses showed no significant association of genotype or allele frequencies of pri-miR-143 rs41291957 A/G polymorphism with the CHD cases in overall or various subtypes compared with the control group.
|
24752771 |
2014 |
|
rs41291957
|
MIR143;MIR145;CARMN
|
Congenital heart disease
|
|
0.010 |
GeneticVariation |
BEFREE |
Therefore, the authors hypothesized that rs41291957 in pri-miR-143 might be involved in the risk of sporadic congenital heart disease (CHD).
|
24752771 |
2014 |
|
rs41291957
|
MIR143;MIR145;CARMN
|
Neoplasms
|
|
0.010 |
GeneticVariation |
BEFREE |
When stratification analysis was done by different variables, such as tumor size, tumor site, differentiated status, clinical stage, and metastasis status, we found that patients with the mutant allele of rs41291957 had an increased risk to develop a tumor size larger than 5 cm.
|
23628392 |
2013 |
|
rs41291957
|
MIR143;MIR145;CARMN
|
Neoplasm Metastasis
|
|
0.010 |
GeneticVariation |
BEFREE |
When stratification analysis was done by different variables, such as tumor size, tumor site, differentiated status, clinical stage, and metastasis status, we found that patients with the mutant allele of rs41291957 had an increased risk to develop a tumor size larger than 5 cm.
|
23628392 |
2013 |