rs2910164
|
MIR146A;MIR3142HG
|
Rheumatoid Arthritis
|
|
0.100 |
GeneticVariation |
BEFREE |
We first investigated the association between the SNPs (rs2910164 G>C and rs3746444 T>C) in the pre-miRNA (hsa-mir-146a and hsa-mir-499) and RA in a Han Chinese population.
|
21181275 |
2011 |
rs2910164
|
MIR146A;MIR3142HG
|
Rheumatoid Arthritis
|
|
0.100 |
GeneticVariation |
BEFREE |
To investigate whether miRNA-499 (rs3746444) and miRNA-146a (rs2910164) genes polymorphisms are independent factors for rheumatoid arthritis (RA) in Egyptians, and whether they influence disease severity and activity.
|
23731641 |
2013 |
rs2910164
|
MIR146A;MIR3142HG
|
Rheumatoid Arthritis
|
|
0.100 |
GeneticVariation |
BEFREE |
These observations prompted us to analyze the potential associations between the miR-146a-3p (rs2910164, G > C) and NFkB1 (rs28362491, ins/del ATTG) polymorphisms and miR-146a-5p expression in patients' sera in relation to clinical outcome of the treatment as well as predisposition to RA.
|
28083614 |
2016 |
rs2910164
|
MIR146A;MIR3142HG
|
Rheumatoid Arthritis
|
|
0.100 |
GeneticVariation |
BEFREE |
Functional studies are required to investigate the exact role of miR-146a rs2910164 during RA.
|
28207326 |
2017 |
rs2910164
|
MIR146A;MIR3142HG
|
Rheumatoid Arthritis
|
|
0.100 |
GeneticVariation |
BEFREE |
MiRNA-146a rs2910164 polymorphism is not associated with RA risk, while miRNA-499 rs3746444 polymorphism is correlated with RA risk.
|
24824381 |
2014 |
rs2910164
|
MIR146A;MIR3142HG
|
Rheumatoid Arthritis
|
|
0.100 |
GeneticVariation |
BEFREE |
Our findings demonstrated that the hsa-mir-499 rs3746444, but not mir-146a rs2910164, polymorphism is associated with an increased RA risk in a sample of the Iranian population.
|
23138379 |
2013 |
rs2910164
|
MIR146A;MIR3142HG
|
Rheumatoid Arthritis
|
|
0.100 |
GeneticVariation |
BEFREE |
<b>Conclusions:</b> The association of miR-146a rs2910164 (G/C) with RA was not found.
|
31235484 |
2019 |
rs2910164
|
MIR146A;MIR3142HG
|
Rheumatoid Arthritis
|
|
0.100 |
GeneticVariation |
BEFREE |
Is the microRNA-146a (rs2910164) polymorphism associated with rheumatoid arthritis? Association of microRNA-146a (rs2910164) polymorphism and rheumatoid arthritis could depend on gender.
|
25630616 |
2015 |
rs2910164
|
MIR146A;MIR3142HG
|
Rheumatoid Arthritis
|
|
0.100 |
GeneticVariation |
BEFREE |
Serum miRNA-146a was negatively correlated with anti-nuclear antibodies (ANA). miRNA-146a (rs2910164) genotyping revealed that the GG genotype and the frequency of the G allele were significantly higher in RA patients compared to the controls. miRNA-499 (rs3746444), genotyping revealed that the CC genotype and the frequency of the C allele were significantly higher.
|
29700729 |
2018 |
rs2910164
|
MIR146A;MIR3142HG
|
Rheumatoid Arthritis
|
|
0.100 |
GeneticVariation |
BEFREE |
<b>Significance:</b> The miR-146a rs2910164 G > C polymorphism was not associated with susceptibility to RA.
|
30498453 |
2018 |
rs2910164
|
MIR146A;MIR3142HG
|
Rheumatoid Arthritis
|
|
0.100 |
GeneticVariation |
BEFREE |
Our meta-analysis of six case-control studies involving a total of 998 RA cases and 1493 controls identified no significant association between mir-146a rs2910164 and RA, with an overall OR of 0.843 (95% CI=0.642-1.105; CC vs. GG).
|
25218914 |
2016 |
rs2910164
|
MIR146A;MIR3142HG
|
Rheumatoid Arthritis
|
|
0.100 |
GeneticVariation |
BEFREE |
The aim of this study was to detect the association between 2 single nucleotide polymorphisms (SNPs), rs2910164 G>C and rs3746444 T>C, in pre-miRNA (hsa-mir-146a and hsa-mir-499) and the chronic inflammation in the Chinese Han population with rheumatoid arthritis (RA).
|
22019503 |
2012 |
rs2910164
|
MIR146A;MIR3142HG
|
Rheumatoid Arthritis
|
|
0.100 |
GeneticVariation |
BEFREE |
The aim of the present study was to reveal if there is any association of miRNA-146a variant rs2910164 and the two interleukin (IL) 1 receptor associated kinase (IRAK1, a target gene of mir-146a) polymorphisms rs3027898 and rs1059703 with RA predisposition.
|
20870441 |
2010 |
rs2910164
|
MIR146A;MIR3142HG
|
Rheumatoid Arthritis
|
|
0.100 |
GeneticVariation |
BEFREE |
MiRNA-146a rs2910164 and IRAK1 rs3027898 polymorphisms were a risk factor for predisposition to RA in codominant and dominant tested inheritance models, while, the miRNA-499 rs3746444 and PADI4 rs1748033 polymorphisms were a risk factor in codominant and recessive one.
|
29734142 |
2018 |