MIR21, microRNA 21, 406991

N. diseases: 726; N. variants: 2
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs13137
rs13137
Entrez Id: 81671;406991
Gene Symbol: VMP1;MIR21
VMP1;MIR21
CUI: C0036690
Disease:
Septicemia
0.010 GeneticVariation BEFREE The T allele of the miR-21 SNP rs13137 and the T allele of the miR-145 SNP rs353291 (OR = 0.685, 95% CI = 0.566-0.820, P < .001) were found to be a protective factor for sepsis (OR = 0.755, 95% CI = 0.632-0.896, P < .001). 31415369 2019
dbSNP: rs13137
rs13137
Entrez Id: 81671;406991
Gene Symbol: VMP1;MIR21
VMP1;MIR21
CUI: C0243026
Disease:
Sepsis
0.010 GeneticVariation BEFREE The T allele of the miR-21 SNP rs13137 and the T allele of the miR-145 SNP rs353291 (OR = 0.685, 95% CI = 0.566-0.820, P < .001) were found to be a protective factor for sepsis (OR = 0.755, 95% CI = 0.632-0.896, P < .001). 31415369 2019
dbSNP: rs1292037
rs1292037
Entrez Id: 81671;406991
Gene Symbol: VMP1;MIR21
VMP1;MIR21
CUI: C0686619
Disease:
Secondary malignant neoplasm of lymph node
0.010 GeneticVariation BEFREE The influencing factors of resistance to cisplatin plus paclitaxel included maximum lesion diameter, tumor stage, lymph node metastasis and rs1292037 (odds ratio [OR] = 14.047, 95% CI = 5.694-34.653; OR = 5.873, 95% CI = 3.104-11.110; OR = 3.574, 95% CI = 1.554-8.216; OR = 2.449, 95% CI = 1.052-5.705). 30447706 2018
dbSNP: rs1292037
rs1292037
Entrez Id: 81671;406991
Gene Symbol: VMP1;MIR21
VMP1;MIR21
CUI: C0027651
Disease:
Neoplasms
0.010 GeneticVariation BEFREE The risk factors of prognosis included rs1292037 (A > G) locus, tumor stage, maximum lesion diameter and lymph node metastasis (hazard ratio [HR] = 1.819, 95% CI = 1.127-2.935; HR = 1.504, 95% CI = 1.070-2.114; HR = 1.671, 95% CI = 1.038-2.689; HR = 3.043, 95% CI = 1.783-5.193). 30447706 2018
dbSNP: rs1292037
rs1292037
Entrez Id: 81671;406991
Gene Symbol: VMP1;MIR21
VMP1;MIR21
CUI: C0007847
Disease:
Malignant tumor of cervix
0.010 GeneticVariation BEFREE In addition to that, the G allele at rs1292037 (A > G) locus increases the risk of preoperative chemoresistance to cisplatin plus paclitaxel and is a poor prognostic factor for patients with CC. 30447706 2018
dbSNP: rs1292037
rs1292037
Entrez Id: 81671;406991
Gene Symbol: VMP1;MIR21
VMP1;MIR21
CUI: C4048328
Disease:
cervical cancer
0.010 GeneticVariation BEFREE In addition to that, the G allele at rs1292037 (A > G) locus increases the risk of preoperative chemoresistance to cisplatin plus paclitaxel and is a poor prognostic factor for patients with CC. 30447706 2018
dbSNP: rs1292037
rs1292037
Entrez Id: 81671;406991
Gene Symbol: VMP1;MIR21
VMP1;MIR21
CUI: C0302592
Disease:
Cervix carcinoma
0.010 GeneticVariation BEFREE In addition to that, the G allele at rs1292037 (A > G) locus increases the risk of preoperative chemoresistance to cisplatin plus paclitaxel and is a poor prognostic factor for patients with CC. 30447706 2018
dbSNP: rs13137
rs13137
Entrez Id: 81671;406991
Gene Symbol: VMP1;MIR21
VMP1;MIR21
CUI: C0302592
Disease:
Cervix carcinoma
0.010 GeneticVariation BEFREE We investigated correlations of miR-21 gene polymorphisms including rs1292037 (A > G) and rs13137 (A > T) with the chemosensitivity to cisplatin plus paclitaxel, and prognosis before cervical cancer (CC) surgery, which may provide a novel target for prevention and treatment of CC. 30447706 2018
dbSNP: rs13137
rs13137
Entrez Id: 81671;406991
Gene Symbol: VMP1;MIR21
VMP1;MIR21
CUI: C4048328
Disease:
cervical cancer
0.010 GeneticVariation BEFREE We investigated correlations of miR-21 gene polymorphisms including rs1292037 (A > G) and rs13137 (A > T) with the chemosensitivity to cisplatin plus paclitaxel, and prognosis before cervical cancer (CC) surgery, which may provide a novel target for prevention and treatment of CC. 30447706 2018
dbSNP: rs13137
rs13137
Entrez Id: 81671;406991
Gene Symbol: VMP1;MIR21
VMP1;MIR21
CUI: C0007847
Disease:
Malignant tumor of cervix
0.010 GeneticVariation BEFREE We investigated correlations of miR-21 gene polymorphisms including rs1292037 (A > G) and rs13137 (A > T) with the chemosensitivity to cisplatin plus paclitaxel, and prognosis before cervical cancer (CC) surgery, which may provide a novel target for prevention and treatment of CC. 30447706 2018
dbSNP: rs1292037
rs1292037
Entrez Id: 81671;406991
Gene Symbol: VMP1;MIR21
VMP1;MIR21
CUI: C0948008
Disease:
Ischemic stroke
0.010 GeneticVariation BEFREE We investigated whether three common microRNA polymorphisms (miR-21T>C [rs1292037], miR-126G>A [rs4636297] and miR-605T>C [rs2043556]) were associated with ischemic stroke (IS) risk in a Chinese population. 29221163 2017