MDM2, MDM2 proto-oncogene, 4193

N. diseases: 702; N. variants: 30
Disease: Primary malignant neoplasm ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs937283
rs937283
Entrez Id: 4193
Gene Symbol: MDM2
MDM2
CUI: C1306459
Disease:
Primary malignant neoplasm 		0.030 GeneticVariation BEFREE Moreover, results of meta-analysis demonstrated that rs937283 was significantly associated with cancer</span> susceptibility, and this significant association remained in Asian (Chinese) population, but not in Caucasian population. 30244662 2018
dbSNP: rs937283
rs937283
Entrez Id: 4193
Gene Symbol: MDM2
MDM2
CUI: C1306459
Disease:
Primary malignant neoplasm 		0.030 GeneticVariation BEFREE Moreover, the meta-analysis according to cancer</span> types revealed that rs937283 was associated with retinoblastoma risk, but not squamous cell carcinoma risk. 29777315 2018
dbSNP: rs937283
rs937283
Entrez Id: 4193
Gene Symbol: MDM2
MDM2
CUI: C1306459
Disease:
Primary malignant neoplasm 		0.030 GeneticVariation BEFREE Three MDM2 SNPs(rs937283, rs2270744 and rs769412) have previously been suggested to be positively correlated with cancer. 27506496 2016