MDM2, MDM2 proto-oncogene, 4193

N. diseases: 702; N. variants: 30
Disease: Primary malignant neoplasm of lung ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2279744
rs2279744
Entrez Id: 4193
Gene Symbol: MDM2
MDM2
CUI: C1306460
Disease:
Primary malignant neoplasm of lung 		0.020 GeneticVariation BEFREE The polymorphism SNP309 (rs2279744) in the promoter region of the MDM2 gene has been shown to alter protein expression and may play a role in the susceptibility to lung cancer. 18433484 2008
dbSNP: rs2279744
rs2279744
Entrez Id: 4193
Gene Symbol: MDM2
MDM2
CUI: C1306460
Disease:
Primary malignant neoplasm of lung 		0.020 GeneticVariation BEFREE We investigated the association between genetic variation in the promoter region of MDM2 (c.-5+309G>T, rs2279744:g.G>T) and the coding region of TP53 (c.215G>C, rs1042522:g.G>C, designated Arg72Pro) and the risk of developing lung cancer. 16287156 2006