MEF2D, myocyte enhancer factor 2D, 4209

N. diseases: 72; N. variants: 10
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2274316
rs2274316
Entrez Id: 4209
Gene Symbol: MEF2D
MEF2D
CUI: C0149931
Disease:
Migraine Disorders
0.820 GeneticVariation BEFREE Conclusion Migraine response to PACAP38 infusion in migraine without aura patients is not associated with high family load or the risk allele of rs2274316 ( MEF2D). 26994299 2017
dbSNP: rs2274316
rs2274316
Entrez Id: 4209
Gene Symbol: MEF2D
MEF2D
CUI: C0149931
Disease:
Migraine Disorders
0.820 GeneticVariation BEFREE At one extreme, SNPs rs6790925 (near TGFBR2) and rs2274316 (MEF2D) were not associated with migraine overall, MA, or MO but were selective for migraine sub-classified by the presence of one or more of the additional migraine features. 24852292 2014
dbSNP: rs2274316
rs2274316
Entrez Id: 4209
Gene Symbol: MEF2D
MEF2D
CUI: C0149931
Disease:
Migraine Disorders
C 0.820 GeneticVariation GWASCAT Genome-wide meta-analysis identifies new susceptibility loci for migraine. 23793025 2013
dbSNP: rs2274316
rs2274316
Entrez Id: 4209
Gene Symbol: MEF2D
MEF2D
CUI: C0149931
Disease:
Migraine Disorders
C 0.820 GeneticVariation GWASDB Genome-wide meta-analysis identifies new susceptibility loci for migraine. 23793025 2013
dbSNP: rs2274316
rs2274316
Entrez Id: 4209
Gene Symbol: MEF2D
MEF2D
CUI: C0149931
Disease:
Migraine Disorders
0.820 GeneticVariation GWASDB Genome-wide association analysis identifies susceptibility loci for migraine without aura. 22683712 2012
dbSNP: rs1925950
rs1925950
Entrez Id: 4209
Gene Symbol: MEF2D
MEF2D
CUI: C0149931
Disease:
Migraine Disorders
G 0.800 GeneticVariation GWASCAT Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine. 27322543 2016
dbSNP: rs3790455
rs3790455
Entrez Id: 4209
Gene Symbol: MEF2D
MEF2D
CUI: C0149931
Disease:
Migraine Disorders
0.800 GeneticVariation GWASDB Genome-wide meta-analysis identifies new susceptibility loci for migraine. 23793025 2013
dbSNP: rs1925950
rs1925950
Entrez Id: 4209
Gene Symbol: MEF2D
MEF2D
CUI: C0149931
Disease:
Migraine Disorders
0.800 GeneticVariation GWASDB Genome-wide association analysis identifies susceptibility loci for migraine without aura. 22683712 2012
dbSNP: rs3790455
rs3790455
Entrez Id: 4209
Gene Symbol: MEF2D
MEF2D
CUI: C0149931
Disease:
Migraine Disorders
C 0.800 GeneticVariation GWASDB Genome-wide association analysis identifies susceptibility loci for migraine without aura. 22683712 2012
dbSNP: rs3790455
rs3790455
Entrez Id: 4209
Gene Symbol: MEF2D
MEF2D
CUI: C0149931
Disease:
Migraine Disorders
C 0.800 GeneticVariation GWASCAT Genome-wide association analysis identifies susceptibility loci for migraine without aura. 22683712 2012
dbSNP: rs10908505
rs10908505
Entrez Id: 4209
Gene Symbol: MEF2D
MEF2D
CUI: C0005890
Disease:
Body Height
0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs2274319
rs2274319
Entrez Id: 4209
Gene Symbol: MEF2D
MEF2D
CUI: C1305855
Disease:
Body mass index
T 0.700 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry. 30239722 2019
dbSNP: rs1050316
rs1050316
Entrez Id: 4209
Gene Symbol: MEF2D
MEF2D
CUI: C0018681
Disease:
Headache
T 0.700 GeneticVariation GWASCAT A Genome-Wide Association Study Finds Genetic Associations with Broadly-Defined Headache in UK Biobank (N=223,773). 29397368 2018
dbSNP: rs1050316
rs1050316
Entrez Id: 4209
Gene Symbol: MEF2D
MEF2D
CUI: C0032181
Disease:
Platelet Count measurement
T 0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
dbSNP: rs1171563
rs1171563
Entrez Id: 4209
Gene Symbol: MEF2D
MEF2D
CUI: C1821417
Disease:
RESTING HEART RATE
G 0.700 GeneticVariation GWASCAT Identification of genomic loci associated with resting heart rate and shared genetic predictors with all-cause mortality. 27798624 2016
dbSNP: rs2274319
rs2274319
Entrez Id: 4209
Gene Symbol: MEF2D
MEF2D
CUI: C0149931
Disease:
Migraine Disorders
0.700 GeneticVariation GWASCAT Detection and interpretation of shared genetic influences on 42 human traits. 27182965 2016
dbSNP: rs202206511
rs202206511
Entrez Id: 4209
Gene Symbol: MEF2D
MEF2D
CUI: C0149931
Disease:
Migraine Disorders
0.700 GeneticVariation GWASDB Genome-wide meta-analysis identifies new susceptibility loci for migraine. 23793025 2013
dbSNP: rs1050316
rs1050316
Entrez Id: 4209
Gene Symbol: MEF2D
MEF2D
CUI: C0149931
Disease:
Migraine Disorders
0.700 GeneticVariation GWASDB Genome-wide association analysis identifies susceptibility loci for migraine without aura. 22683712 2012
dbSNP: rs202206511
rs202206511
Entrez Id: 4209
Gene Symbol: MEF2D
MEF2D
CUI: C0149931
Disease:
Migraine Disorders
C 0.700 GeneticVariation GWASDB Genome-wide association analysis identifies susceptibility loci for migraine without aura. 22683712 2012
dbSNP: rs3790459
rs3790459
Entrez Id: 4209
Gene Symbol: MEF2D
MEF2D
CUI: C0149931
Disease:
Migraine Disorders
0.700 GeneticVariation GWASDB Genome-wide association analysis identifies susceptibility loci for migraine without aura. 22683712 2012
dbSNP: rs10908505
rs10908505
Entrez Id: 4209
Gene Symbol: MEF2D
MEF2D
CUI: C0023508
Disease:
White Blood Cell Count procedure
0.700 GeneticVariation GWASDB Genome-wide association study of white blood cell count in 16,388 African Americans: the continental origins and genetic epidemiology network (COGENT). 21738479 2011
dbSNP: rs2274316
rs2274316
Entrez Id: 4209
Gene Symbol: MEF2D
MEF2D
CUI: C0338480
Disease:
Common Migraine
0.020 GeneticVariation BEFREE Sixteen of the patients were carriers of the risk allele rs2274316 ( MEF2D), which confers increased risk of MO and may regulate PACAP38 expression, and 16 were non-carriers. 26994298 2017
dbSNP: rs2274316
rs2274316
Entrez Id: 4209
Gene Symbol: MEF2D
MEF2D
CUI: C0338480
Disease:
Common Migraine
0.020 GeneticVariation BEFREE Conclusion Migraine response to PACAP38 infusion in migraine without aura patients is not associated with high family load or the risk allele of rs2274316 ( MEF2D). 26994299 2017
dbSNP: rs200395694
rs200395694
Entrez Id: 4209
Gene Symbol: MEF2D
MEF2D
CUI: C0024141
Disease:
Lupus Erythematosus, Systemic
0.010 GeneticVariation BEFREE Using targeted re-sequencing of coding and conserved regulatory regions within and around 215 candidate genes selected on the basis of their known role in autoimmunity and genes associated with canine immune-mediated diseases, we identified a rare regulatory variant rs200395694:G > T located in intron 4 of the MEF2D gene encoding the myocyte-specific enhancer factor 2D transcription factor and associated with SLE in Swedish cohorts (504 SLE patients and 839 healthy controls, p = 0.014, CI = 1.1-10). 30459414 2019
dbSNP: rs200395694
rs200395694
Entrez Id: 4209
Gene Symbol: MEF2D
MEF2D
CUI: C0004364
Disease:
Autoimmune Diseases
0.010 GeneticVariation BEFREE Using targeted re-sequencing of coding and conserved regulatory regions within and around 215 candidate genes selected on the basis of their known role in autoimmunity and genes associated with canine immune-mediated diseases, we identified a rare regulatory variant rs200395694:G > T located in intron 4 of the MEF2D gene encoding the myocyte-specific enhancer factor 2D transcription factor and associated with SLE in Swedish cohorts (504 SLE patients and 839 healthy controls, p = 0.014, CI = 1.1-10). 30459414 2019