MGMT, O-6-methylguanine-DNA methyltransferase, 4255

N. diseases: 444; N. variants: 24
Disease: Familial multiple trichoepitheliomata ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs12268840
rs12268840
Entrez Id: 4255
Gene Symbol: MGMT
MGMT
CUI: C1275122
Disease:
Familial multiple trichoepitheliomata 		0.010 GeneticVariation BEFREE Homozygous carriers of MGMT rs12268840 with frequent acid reflux had significantly higher risks of EAC (OR 15.5, 95% CI 5.8-42) than expected under an additive model, consistent with biological interaction (S = 3.3, 95% CI 1.1-10). 18386788 2008