|
rs755622
|
MIF;MIF-AS1
|
Arthritis
|
|
0.030 |
GeneticVariation |
BEFREE |
A second MIF promoter polymorphism comprises a G-to-C single nucleotide polymorphism (SNP) at position -173 (rs755622), which is in strong linkage disequilibrium with -794 7-CATT and is associated with arthritis clinical severity and higher serum and synovial fluid MIF levels.
|
31745872 |
2020 |
|
rs755622
|
MIF;MIF-AS1
|
Arthritis
|
|
0.030 |
GeneticVariation |
BEFREE |
Single nucleotide polymorphism (SNP) -173 G/C (rs755622) on <i>MIF</i> gene has been associated with numerous diseases, such as arthritis and cancer.
|
29545822 |
2018 |
|
rs755622
|
MIF;MIF-AS1
|
Arthritis
|
|
0.030 |
GeneticVariation |
BEFREE |
A significantly lower frequency of the G allele of rs755622 was observed in the oral aphthae, genital ulceration, hypopyon, and arthritis subgroups compared with controls (P(c) < 0.05).
|
22939113 |
2012 |
|
rs755622
|
MIF;MIF-AS1
|
Rheumatoid Arthritis
|
|
0.020 |
GeneticVariation |
BEFREE |
The aim of this study was to evaluate the association of MIF promoter polymorphisms (-794CATT<sub>5-8</sub> rs5844572 and -173G > C, rs755622), circulating MIF levels, and mRNA expression with RA susceptibility and disease activity.
|
31701681 |
2020 |
|
rs5844572
|
MIF;MIF-AS1
|
Autoimmune Diseases
|
|
0.020 |
GeneticVariation |
BEFREE |
It is suggested that MIF participates in the amplification of the proinflammatory process in SSc; moreover, the promoter polymorphisms - 794 CATT<sub>5-8</sub> (rs5844572) and - 173G>C (rs755622) in the MIF gene have been associated with an increase in MIF serum levels in several autoimmune diseases.
|
30747392 |
2019 |
|
rs755622
|
MIF;MIF-AS1
|
Autoimmune Diseases
|
|
0.020 |
GeneticVariation |
BEFREE |
It is suggested that MIF participates in the amplification of the proinflammatory process in SSc; moreover, the promoter polymorphisms - 794 CATT<sub>5-8</sub> (rs5844572) and - 173G>C (rs755622) in the MIF gene have been associated with an increase in MIF serum levels in several autoimmune diseases.
|
30747392 |
2019 |
|
rs755622
|
MIF;MIF-AS1
|
Multiple Sclerosis
|
|
0.020 |
GeneticVariation |
BEFREE |
Therefore, we decided to investigate the genetic association of -794 CATT<sub>5-8</sub> (rs5844572) and -173 G>C (rs755622) MIF polymorphisms with MS, clinical variables and MIF serum levels in the population of western Mexico.
|
29661540 |
2018 |
|
rs755622
|
MIF;MIF-AS1
|
Primary malignant neoplasm
|
|
0.020 |
GeneticVariation |
BEFREE |
Single nucleotide polymorphism (SNP) -173 G/C (rs755622) on <i>MIF</i> gene has been associated with numerous diseases, such as arthritis and cancer.
|
29545822 |
2018 |
|
rs755622
|
MIF;MIF-AS1
|
Multiple Sclerosis
|
|
0.020 |
GeneticVariation |
BEFREE |
The results show that the minor allele frequency of rs755622 and expression of <i>DDT</i> are significantly increased in males for MS subjects and this minor allele variant can significantly upregulate <i>DDT</i> expression for males but not females, which suggests that the regulation of <i>DDT</i> expression level by rs755622 can affect MS progression in males.
|
30140701 |
2018 |
|
rs755622
|
MIF;MIF-AS1
|
Malignant Neoplasms
|
|
0.020 |
GeneticVariation |
BEFREE |
Single nucleotide polymorphism (SNP) -173 G/C (rs755622) on <i>MIF</i> gene has been associated with numerous diseases, such as arthritis and cancer.
|
29545822 |
2018 |
|
rs755622
|
MIF;MIF-AS1
|
Childhood Acute Lymphoblastic Leukemia
|
|
0.020 |
GeneticVariation |
BEFREE |
The results of the present study indicate that the MIF-173G/C (rs755622) polymorphism is a risk factor for childhood ALL development with respect to both homozygous and combined polymorphic genotypes.
|
29996006 |
2018 |
|
rs5844572
|
MIF;MIF-AS1
|
Autoimmune Diseases
|
|
0.020 |
GeneticVariation |
BEFREE |
Two polymorphisms, rs755622 and rs5844572, in the promoter region of the macrophage migration inhibitory factor (MIF) gene influence the basal and/or induced transcriptional activity and have been linked to several inflammatory and autoimmune diseases.
|
28657145 |
2017 |
|
rs755622
|
MIF;MIF-AS1
|
Autoimmune Diseases
|
|
0.020 |
GeneticVariation |
BEFREE |
Two polymorphisms, rs755622 and rs5844572, in the promoter region of the macrophage migration inhibitory factor (MIF) gene influence the basal and/or induced transcriptional activity and have been linked to several inflammatory and autoimmune diseases.
|
28657145 |
2017 |
|
rs755622
|
MIF;MIF-AS1
|
Primary malignant neoplasm
|
|
0.020 |
GeneticVariation |
BEFREE |
Macrophage migration inhibitory factor (MIF) -173G/C (rs755622) gene polymorphism has been associated with cancer risk.
|
26107210 |
2015 |
|
rs755622
|
MIF;MIF-AS1
|
Malignant Neoplasms
|
|
0.020 |
GeneticVariation |
BEFREE |
Macrophage migration inhibitory factor (MIF) -173G/C (rs755622) gene polymorphism has been associated with cancer risk.
|
26107210 |
2015 |
|
rs755622
|
MIF;MIF-AS1
|
Rheumatoid Arthritis
|
|
0.020 |
GeneticVariation |
BEFREE |
The aim of this study was to evaluate the association between macrophage migration inhibitory factor (MIF) -173G/C (rs755622), mannose-binding lectin (MBL2) exon 1 codon 54 (rs1800450) gene polymorphisms and rheumatoid arthritis (RA) susceptibility in ethnically different populations.
|
22820623 |
2012 |
|
rs755622
|
MIF;MIF-AS1
|
Childhood Acute Lymphoblastic Leukemia
|
|
0.020 |
GeneticVariation |
BEFREE |
We genotyped the MIF -173G/C polymorphism (rs755622) in 346 ALL cases and 516 cancer-free controls in a Chinese population and found that the variant genotype GC and the combined genotypes GC/CC were associated with a significantly higher risk of childhood ALL [adjusted odds ratio (OR)=1.39, 95% confidence interval (CI)=1.01-1.93 for GC and adjusted OR=1.38, 95% CI=1.01-1.89 for GC/CC].
|
20447688 |
2010 |
|
rs5844572
|
MIF;MIF-AS1
|
Rheumatoid Arthritis
|
|
0.010 |
GeneticVariation |
BEFREE |
The aim of this study was to evaluate the association of MIF promoter polymorphisms (-794CATT<sub>5-8</sub> rs5844572 and -173G > C, rs755622), circulating MIF levels, and mRNA expression with RA susceptibility and disease activity.
|
31701681 |
2020 |
|
rs5844572
|
MIF;MIF-AS1
|
Systemic Scleroderma
|
|
0.010 |
GeneticVariation |
BEFREE |
It is suggested that MIF participates in the amplification of the proinflammatory process in SSc; moreover, the promoter polymorphisms - 794 CATT<sub>5-8</sub> (rs5844572) and - 173G>C (rs755622) in the MIF gene have been associated with an increase in MIF serum levels in several autoimmune diseases.
|
30747392 |
2019 |
|
rs755622
|
MIF;MIF-AS1
|
Alopecia
|
|
0.010 |
GeneticVariation |
BEFREE |
Macrophage migration inhibitory factor polymorphism (rs755622) in alopecia areata: a possible role in disease prevention.
|
31154458 |
2019 |
|
rs755622
|
MIF;MIF-AS1
|
Alopecia Areata
|
|
0.010 |
GeneticVariation |
BEFREE |
Macrophage migration inhibitory factor polymorphism (rs755622) in alopecia areata: a possible role in disease prevention.
|
31154458 |
2019 |
|
rs755622
|
MIF;MIF-AS1
|
Systemic Scleroderma
|
|
0.010 |
GeneticVariation |
BEFREE |
It is suggested that MIF participates in the amplification of the proinflammatory process in SSc; moreover, the promoter polymorphisms - 794 CATT<sub>5-8</sub> (rs5844572) and - 173G>C (rs755622) in the MIF gene have been associated with an increase in MIF serum levels in several autoimmune diseases.
|
30747392 |
2019 |
|
rs755622
|
MIF;MIF-AS1
|
Nephrotic Syndrome
|
|
0.010 |
GeneticVariation |
BEFREE |
The current study aimed to evaluate the relationshipbetween MIF -173 G>C (rs755622) variant and susceptibility to NS.
|
31422388 |
2019 |
|
rs5844572
|
MIF;MIF-AS1
|
Granulomatosis with polyangiitis
|
|
0.010 |
GeneticVariation |
BEFREE |
The human study involved 1,077 patients with GPA and healthy controls whose serum was genotyped by capillary electrophoresis for the MIF -794 CATT<sub>5-8</sub> promoter microsatellite (rs5844572).
|
29953750 |
2018 |
|
rs5844572
|
MIF;MIF-AS1
|
Multiple Sclerosis
|
|
0.010 |
GeneticVariation |
BEFREE |
Therefore, we decided to investigate the genetic association of -794 CATT<sub>5-8</sub> (rs5844572) and -173 G>C (rs755622) MIF polymorphisms with MS, clinical variables and MIF serum levels in the population of western Mexico.
|
29661540 |
2018 |