rs63750437
|
Entrez Id: |
4292 |
Gene Symbol: |
MLH1 |
MLH1
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
A |
0.700 |
CausalMutation |
CLINVAR |
Application of a 5-tiered scheme for standardized classification of 2,360 unique mismatch repair gene variants in the InSiGHT locus-specific database.
|
24362816 |
2014 |
rs63750437
|
Entrez Id: |
4292 |
Gene Symbol: |
MLH1 |
MLH1
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
A |
0.700 |
CausalMutation |
CLINVAR |
Calibration of multiple in silico tools for predicting pathogenicity of mismatch repair gene missense substitutions.
|
22949387 |
2013 |
rs63750437
|
Entrez Id: |
4292 |
Gene Symbol: |
MLH1 |
MLH1
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
A |
0.700 |
CausalMutation |
CLINVAR |
Functional analysis of human MLH1 variants using yeast and in vitro mismatch repair assays.
|
17510385 |
2007 |
rs63750437
|
Entrez Id: |
4292 |
Gene Symbol: |
MLH1 |
MLH1
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
A |
0.700 |
CausalMutation |
CLINVAR |
Spectrum and frequencies of mutations in MSH2 and MLH1 identified in 1,721 German families suspected of hereditary nonpolyposis colorectal cancer.
|
15849733 |
2005 |
rs63750437
|
Entrez Id: |
4292 |
Gene Symbol: |
MLH1 |
MLH1
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
A |
0.700 |
CausalMutation |
CLINVAR |
A yeast two-hybrid assay provides a simple way to evaluate the vast majority of hMLH1 germ-line mutations.
|
12810663 |
2003 |
rs63750437
|
Entrez Id: |
4292 |
Gene Symbol: |
MLH1 |
MLH1
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
A |
0.700 |
CausalMutation |
CLINVAR |
Mutations in the MutSalpha interaction interface of MLH1 can abolish DNA mismatch repair.
|
17135187 |
2006 |
rs63750437
|
Entrez Id: |
4292 |
Gene Symbol: |
MLH1 |
MLH1
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
A |
0.700 |
CausalMutation |
CLINVAR |
Germline HNPCC gene variants have little influence on the risk for sporadic colorectal cancer.
|
9032648 |
1997 |
rs63750437
|
Entrez Id: |
4292 |
Gene Symbol: |
MLH1 |
MLH1
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
A |
0.700 |
CausalMutation |
CLINVAR |
Functional significance and clinical phenotype of nontruncating mismatch repair variants of MLH1.
|
16083711 |
2005 |
rs63750437
|
Entrez Id: |
4292 |
Gene Symbol: |
MLH1 |
MLH1
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
A |
0.700 |
CausalMutation |
CLINVAR |
Accurate classification of MLH1/MSH2 missense variants with multivariate analysis of protein polymorphisms-mismatch repair (MAPP-MMR).
|
18383312 |
2008 |
rs63750437
|
Entrez Id: |
4292 |
Gene Symbol: |
MLH1 |
MLH1
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
A |
0.700 |
CausalMutation |
CLINVAR |
Functional analysis of MLH1 mutations linked to hereditary nonpolyposis colon cancer.
|
11793442 |
2002 |
rs63750437
|
Entrez Id: |
4292 |
Gene Symbol: |
MLH1 |
MLH1
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
A |
0.700 |
CausalMutation |
CLINVAR |
The effect of genetic background on the function of Saccharomyces cerevisiae mlh1 alleles that correspond to HNPCC missense mutations.
|
17210669 |
2007 |
rs63750437
|
Entrez Id: |
4292 |
Gene Symbol: |
MLH1 |
MLH1
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
A |
0.700 |
CausalMutation |
CLINVAR |
Missense variants in hMLH1 identified in patients from the German HNPCC consortium and functional studies.
|
21404117 |
2011 |