rs121912953
×
Entrez Id:
4313
Gene Symbol:
MMP2
MMP2
TORG-WINCHESTER SYNDROME
0.800
GeneticVariation
UNIPROT
A novel homozygous MMP2 mutation in a family with Winchester syndrome.
16542393
2006
rs121912955
×
Entrez Id:
4313
Gene Symbol:
MMP2
MMP2
TORG-WINCHESTER SYNDROME
0.800
GeneticVariation
UNIPROT
A novel homozygous MMP2 mutation in a family with Winchester syndrome.
16542393
2006
rs121912953
×
Entrez Id:
4313
Gene Symbol:
MMP2
MMP2
TORG-WINCHESTER SYNDROME
0.800
GeneticVariation
UNIPROT
Winchester syndrome caused by a homozygous mutation affecting the active site of matrix metalloproteinase 2.
15691365
2005
rs121912955
×
Entrez Id:
4313
Gene Symbol:
MMP2
MMP2
TORG-WINCHESTER SYNDROME
0.800
GeneticVariation
UNIPROT
Winchester syndrome caused by a homozygous mutation affecting the active site of matrix metalloproteinase 2.
15691365
2005
rs121912953
×
Entrez Id:
4313
Gene Symbol:
MMP2
MMP2
TORG-WINCHESTER SYNDROME
0.800
GeneticVariation
UNIPROT
Mutation of the matrix metalloproteinase 2 gene (MMP2) causes a multicentric osteolysis and arthritis syndrome.
11431697
2001
rs121912955
×
Entrez Id:
4313
Gene Symbol:
MMP2
MMP2
TORG-WINCHESTER SYNDROME
0.800
GeneticVariation
UNIPROT
Mutation of the matrix metalloproteinase 2 gene (MMP2) causes a multicentric osteolysis and arthritis syndrome.
11431697
2001
rs121912953
×
Entrez Id:
4313
Gene Symbol:
MMP2
MMP2
TORG-WINCHESTER SYNDROME
A
0.800
CausalMutation
CLINVAR
rs121912955
×
Entrez Id:
4313
Gene Symbol:
MMP2
MMP2
TORG-WINCHESTER SYNDROME
A
0.800
CausalMutation
CLINVAR
rs243865
×
Entrez Id:
4313
Gene Symbol:
MMP2
MMP2
Lip and Oral Cavity Carcinoma
0.720
GeneticVariation
BEFREE
In this case-control study, MMP2 promoter 1306 (rs243865 ) and -735 (rs2285053) genotypes and their interaction with consumption of areca, cigarettes, and alcohol in determining oral cancer risk were investigated among 788 patients with oral cancer and 956 gender-matched healthy controls.
30504396
2018
rs243865
×
Entrez Id:
4313
Gene Symbol:
MMP2
MMP2
Lip and Oral Cavity Carcinoma
0.720
GeneticVariation
BEFREE
Our data indicated genotypes and alleles in specific SNPs rs9849237, rs243865 and rs1009078 7 with increased/decreased risk to oral cancer .
28595731
2017
rs243865
×
Entrez Id:
4313
Gene Symbol:
MMP2
MMP2
Lip and Oral Cavity Carcinoma
T
0.720
GeneticVariation
CLINVAR
rs142319636
×
Entrez Id:
4313
Gene Symbol:
MMP2
MMP2
Colorectal Carcinoma
G
0.710
GeneticVariation
GWASCAT
We discovered 17 variants across 4 independent regions that merit further investigation due to suggestive CRC associations (P < 1×10(-6)) at 1p34.3 (rs7528276; Odds Ratio (OR) = 1.86 [95% confidence interval (CI): 1.47-2.36); P = 2.5×10(-7)], 2q23.3 (rs1367374; OR = 1.37 (95% CI: 1.21-1.55); P = 4.0×10(-7)), 14q24.2 (rs143046984; OR = 1.65 (95% CI: 1.36-2.01); P = 4.1×10(-7)) and 16q12.2 [rs142319636 ; OR = 1.69 (95% CI: 1.37-2.08); P=7.8×10(-7)].
27207650
2016
rs142319636
×
Entrez Id:
4313
Gene Symbol:
MMP2
MMP2
Colorectal Carcinoma
0.710
GeneticVariation
BEFREE
We discovered 17 variants across 4 independent regions that merit further investigation due to suggestive CRC associations (P < 1×10(-6)) at 1p34.3 (rs7528276; Odds Ratio (OR) = 1.86 [95% confidence interval (CI): 1.47-2.36); P = 2.5×10(-7)], 2q23.3 (rs1367374; OR = 1.37 (95% CI: 1.21-1.55); P = 4.0×10(-7)), 14q24.2 (rs143046984; OR = 1.65 (95% CI: 1.36-2.01); P = 4.1×10(-7)) and 16q12.2 [rs142319636 ; OR = 1.69 (95% CI: 1.37-2.08); P=7.8×10(-7)].
27207650
2016
rs142319636
×
Entrez Id:
4313
Gene Symbol:
MMP2
MMP2
Adenocarcinoma of large intestine
G
0.700
GeneticVariation
GWASCAT
Genome-wide association study of colorectal cancer in Hispanics.
27207650
2016
rs142319636
×
Entrez Id:
4313
Gene Symbol:
MMP2
MMP2
COLORECTAL CANCER, SUSCEPTIBILITY TO, 10
G
0.700
GeneticVariation
GWASCAT
Genome-wide association study of colorectal cancer in Hispanics.
27207650
2016
rs142319636
×
Entrez Id:
4313
Gene Symbol:
MMP2
MMP2
Malignant neoplasm of large intestine
G
0.700
GeneticVariation
GWASCAT
Genome-wide association study of colorectal cancer in Hispanics.
27207650
2016
rs142319636
×
Entrez Id:
4313
Gene Symbol:
MMP2
MMP2
Malignant tumor of colon
G
0.700
GeneticVariation
GWASCAT
Genome-wide association study of colorectal cancer in Hispanics.
27207650
2016
rs142319636
×
Entrez Id:
4313
Gene Symbol:
MMP2
MMP2
COLORECTAL CANCER, SUSCEPTIBILITY TO, 3
G
0.700
GeneticVariation
GWASCAT
Genome-wide association study of colorectal cancer in Hispanics.
27207650
2016
rs142319636
×
Entrez Id:
4313
Gene Symbol:
MMP2
MMP2
COLORECTAL CANCER, SUSCEPTIBILITY TO, 12
G
0.700
GeneticVariation
GWASCAT
Genome-wide association study of colorectal cancer in Hispanics.
27207650
2016
rs142319636
×
Entrez Id:
4313
Gene Symbol:
MMP2
MMP2
COLORECTAL CANCER, SUSCEPTIBILITY TO, 1
G
0.700
GeneticVariation
GWASCAT
Genome-wide association study of colorectal cancer in Hispanics.
27207650
2016
rs142319636
×
Entrez Id:
4313
Gene Symbol:
MMP2
MMP2
Colorectal Neoplasms
G
0.700
GeneticVariation
GWASCAT
Genome-wide association study of colorectal cancer in Hispanics.
27207650
2016
rs121912954
×
Entrez Id:
4313
Gene Symbol:
MMP2
MMP2
TORG-WINCHESTER SYNDROME
A
0.700
CausalMutation
CLINVAR
rs1567378779
×
Entrez Id:
4313
Gene Symbol:
MMP2
MMP2
TORG-WINCHESTER SYNDROME
A
0.700
CausalMutation
CLINVAR
rs243865
×
Entrez Id:
4313
Gene Symbol:
MMP2
MMP2
Oral lesion
T
0.700
GeneticVariation
CLINVAR
rs759302357
×
Entrez Id:
4313
Gene Symbol:
MMP2
MMP2
Colorectal Carcinoma
0.700
GeneticVariation
UNIPROT