Disease: Neoplastic Syndromes, Hereditary ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1555017290
rs1555017290
Entrez Id: 4361
Gene Symbol: MRE11
MRE11
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		T 0.700 GeneticVariation CLINVAR
dbSNP: rs1555018818
rs1555018818
Entrez Id: 4361;54851
Gene Symbol: MRE11;ANKRD49
MRE11;ANKRD49
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		A 0.700 GeneticVariation CLINVAR
dbSNP: rs201572020
rs201572020
Entrez Id: 4361
Gene Symbol: MRE11
MRE11
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		C 0.700 GeneticVariation CLINVAR
dbSNP: rs371077728
rs371077728
Entrez Id: 4361;100302275
Gene Symbol: MRE11;MIR548L
MRE11;MIR548L
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		A 0.700 CausalMutation CLINVAR Utilization of multigene panels in hereditary cancer predisposition testing: analysis of more than 2,000 patients. 24763289 2014
dbSNP: rs371077728
rs371077728
Entrez Id: 4361;100302275
Gene Symbol: MRE11;MIR548L
MRE11;MIR548L
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		A 0.700 CausalMutation CLINVAR Evaluation of ACMG-Guideline-Based Variant Classification of Cancer Susceptibility and Non-Cancer-Associated Genes in Families Affected by Breast Cancer. 27153395 2016
dbSNP: rs371077728
rs371077728
Entrez Id: 4361;100302275
Gene Symbol: MRE11;MIR548L
MRE11;MIR548L
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		A 0.700 CausalMutation CLINVAR Prevalence of mutations in a panel of breast cancer susceptibility genes in BRCA1/2-negative patients with early-onset breast cancer. 25503501 2015
dbSNP: rs587780138
rs587780138
Entrez Id: 4361
Gene Symbol: MRE11
MRE11
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		A 0.700 GeneticVariation CLINVAR Mutations in 12 genes for inherited ovarian, fallopian tube, and peritoneal carcinoma identified by massively parallel sequencing. 22006311 2011
dbSNP: rs587780138
rs587780138
Entrez Id: 4361
Gene Symbol: MRE11
MRE11
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		A 0.700 GeneticVariation CLINVAR Rare disruptive mutations and their contribution to the heritable risk of colorectal cancer. 27329137 2016
dbSNP: rs587781381
rs587781381
Entrez Id: 4361
Gene Symbol: MRE11
MRE11
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		T 0.700 CausalMutation CLINVAR
dbSNP: rs587781384
rs587781384
Entrez Id: 4361
Gene Symbol: MRE11
MRE11
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		A 0.700 CausalMutation CLINVAR Panel Testing for Familial Breast Cancer: Calibrating the Tension Between Research and Clinical Care. 26786923 2016
dbSNP: rs587781442
rs587781442
Entrez Id: 4361
Gene Symbol: MRE11
MRE11
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		TGAAGTGGTAGGAAAAATGTC 0.700 GeneticVariation CLINVAR
dbSNP: rs587781442
rs587781442
Entrez Id: 4361
Gene Symbol: MRE11
MRE11
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		TGAAGTGGTAGGAAAAATGTC 0.700 CausalMutation CLINVAR
dbSNP: rs587781822
rs587781822
Entrez Id: 4361
Gene Symbol: MRE11
MRE11
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		C 0.700 GeneticVariation CLINVAR Germline Variants in Targeted Tumor Sequencing Using Matched Normal DNA. 26556299 2016
dbSNP: rs587781822
rs587781822
Entrez Id: 4361
Gene Symbol: MRE11
MRE11
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		C 0.700 GeneticVariation CLINVAR Memorial Sloan Kettering-Integrated Mutation Profiling of Actionable Cancer Targets (MSK-IMPACT): A Hybridization Capture-Based Next-Generation Sequencing Clinical Assay for Solid Tumor Molecular Oncology. 25801821 2015
dbSNP: rs587781828
rs587781828
Entrez Id: 4361
Gene Symbol: MRE11
MRE11
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		GA 0.700 CausalMutation CLINVAR
dbSNP: rs587782030
rs587782030
Entrez Id: 4361
Gene Symbol: MRE11
MRE11
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		A 0.700 CausalMutation CLINVAR
dbSNP: rs730881752
rs730881752
Entrez Id: 4361
Gene Symbol: MRE11
MRE11
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		C 0.700 CausalMutation CLINVAR
dbSNP: rs745677716
rs745677716
Entrez Id: 4361
Gene Symbol: MRE11
MRE11
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		G 0.700 GeneticVariation CLINVAR Male breast cancer in a multi-gene panel testing cohort: insights and unexpected results. 28008555 2017
dbSNP: rs747832587
rs747832587
Entrez Id: 4361
Gene Symbol: MRE11
MRE11
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		G 0.700 CausalMutation CLINVAR
dbSNP: rs759130031
rs759130031
Entrez Id: 4361
Gene Symbol: MRE11
MRE11
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		T 0.700 CausalMutation CLINVAR Two unrelated patients with MRE11A mutations and Nijmegen breakage syndrome-like severe microcephaly. 21227757 2011
dbSNP: rs767787348
rs767787348
Entrez Id: 4361
Gene Symbol: MRE11
MRE11
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		C 0.700 CausalMutation CLINVAR
dbSNP: rs774277300
rs774277300
Entrez Id: 4361
Gene Symbol: MRE11
MRE11
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		A 0.700 CausalMutation CLINVAR
dbSNP: rs774440500
rs774440500
Entrez Id: 4361
Gene Symbol: MRE11
MRE11
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		GT 0.700 CausalMutation CLINVAR
dbSNP: rs776912688
rs776912688
Entrez Id: 4361
Gene Symbol: MRE11
MRE11
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		C 0.700 CausalMutation CLINVAR
dbSNP: rs779269083
rs779269083
Entrez Id: 4361
Gene Symbol: MRE11
MRE11
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		A 0.700 CausalMutation CLINVAR