MSX1, msh homeobox 1, 4487

N. diseases: 180; N. variants: 21
Disease: Cleft upper lip ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs12532
rs12532
Entrez Id: 4487
Gene Symbol: MSX1
MSX1
CUI: C0008924
Disease:
Cleft upper lip 		0.020 GeneticVariation BEFREE Although MSX1 rs3775261 polymorphism was not a risk factor for the disease, the rs12532 AG and rs12532 GG genotypes were associated with NS-CL/P risk (OR = 2.82, 95% CI = 1.55-5.15, P = .001; and OR = 8.42, 95% CI = 2.26-31.29, P = .004, respectively). 23231047 2013
dbSNP: rs12532
rs12532
Entrez Id: 4487
Gene Symbol: MSX1
MSX1
CUI: C0008924
Disease:
Cleft upper lip 		0.020 GeneticVariation BEFREE No significant association was found between NSOC and rs3821949 or rs12532 in MSX1 gene, whereas an association was observed between the P147Q variant and cleft lip with cleft palate in the case-control analysis. 21689018 2011