DisGeNET - a database of gene-disease associations

MTHFD1, methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1, 4522

N. diseases: 121; N. variants: 20

Disease: Childhood Acute Lymphoblastic Leukemia ×

Variant: rs1076991 ×

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Disease

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs1076991

Entrez Id:	4522
Gene Symbol:	MTHFD1

MTHFD1

CUI:	C0023452
Disease:

Childhood Acute Lymphoblastic Leukemia

0.010

GeneticVariation

BEFREE

The genotype distribution of the MTHFD1 rs1076991 differed significantly between the ALL and control population.

23940529

2013