MX1, MX dynamin like GTPase 1, 4599

N. diseases: 71; N. variants: 7
Disease: Multiple Sclerosis ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs17000900
rs17000900
Entrez Id: 4599
Gene Symbol: MX1
MX1
CUI: C0026769
Disease:
Multiple Sclerosis 		0.020 GeneticVariation BEFREE In the present case-control study, we evaluated the association between three SNPs at nt -123 (A or C, rs17000900), nt -88 (G or T, rs2071430), and nt +20 (A or C, rs464138) and MS risk as well as treatment response in a population of Iranian MS patients including 146 IFNβ responders and 85 non-responders as well as 180 healthy controls. 28386647 2017
dbSNP: rs17000900
rs17000900
Entrez Id: 4599
Gene Symbol: MX1
MX1
CUI: C0026769
Disease:
Multiple Sclerosis 		0.020 GeneticVariation BEFREE The objective of this study was to evaluate the associations between two MXA promoter region single nucleotide polymorphisms (rs2071430 and rs17000900) and the gene expression responses, clinical and MRI phenotypes in IFN-beta treated MS patients. 17126411 2007