Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs121918683
rs121918683
Entrez Id: 4609;100270680
Gene Symbol: MYC;CASC11
MYC;CASC11
CUI: C0006413
Disease:
Burkitt Lymphoma 		0.700 GeneticVariation UNIPROT
dbSNP: rs121918685
rs121918685
Entrez Id: 4609;100270680
Gene Symbol: MYC;CASC11
MYC;CASC11
CUI: C0006413
Disease:
Burkitt Lymphoma 		0.700 GeneticVariation UNIPROT
dbSNP: rs28933407
rs28933407
Entrez Id: 4609;100270680
Gene Symbol: MYC;CASC11
MYC;CASC11
CUI: C0006413
Disease:
Burkitt Lymphoma 		0.700 GeneticVariation UNIPROT
dbSNP: rs4645959
rs4645959
Entrez Id: 4609;100270680
Gene Symbol: MYC;CASC11
MYC;CASC11
CUI: C0006142
Disease:
Malignant neoplasm of breast 		0.010 GeneticVariation BEFREE A joint analysis of the Polish and the German study population revealed a 54% increased risk for breast cancer associated with the heterozygous Asn11Ser variant (OR = 1.54, 95% CI 1.05-2.26, p = 0.028). 15929079 2005
dbSNP: rs4645959
rs4645959
Entrez Id: 4609;100270680
Gene Symbol: MYC;CASC11
MYC;CASC11
CUI: C0678222
Disease:
Breast Carcinoma 		0.010 GeneticVariation BEFREE A joint analysis of the Polish and the German study population revealed a 54% increased risk for breast cancer associated with the heterozygous Asn11Ser variant (OR = 1.54, 95% CI 1.05-2.26, p = 0.028). 15929079 2005
dbSNP: rs747141352
rs747141352
Entrez Id: 4609;100270680
Gene Symbol: MYC;CASC11
MYC;CASC11
CUI: C0278879
Disease:
Childhood Burkitt Lymphoma 		0.010 GeneticVariation BEFREE Among the 78 BLs in this series, an additional five had RHOA mutations resulting in a total incidence of 7/82 (8.5%) with c.14G>A (p.R5Q) being present in three cases. 25044415 2014
dbSNP: rs747141352
rs747141352
Entrez Id: 4609;100270680
Gene Symbol: MYC;CASC11
MYC;CASC11
CUI: C0006413
Disease:
Burkitt Lymphoma 		0.010 GeneticVariation BEFREE Among the 78 BLs in this series, an additional five had RHOA mutations resulting in a total incidence of 7/82 (8.5%) with c.14G>A (p.R5Q) being present in three cases. 25044415 2014
dbSNP: rs747141352
rs747141352
Entrez Id: 4609;100270680
Gene Symbol: MYC;CASC11
MYC;CASC11
CUI: C0278764
Disease:
Adult Burkitt Lymphoma 		0.010 GeneticVariation BEFREE Among the 78 BLs in this series, an additional five had RHOA mutations resulting in a total incidence of 7/82 (8.5%) with c.14G>A (p.R5Q) being present in three cases. 25044415 2014
dbSNP: rs4645959
rs4645959
Entrez Id: 4609;100270680
Gene Symbol: MYC;CASC11
MYC;CASC11
CUI: C0346153
Disease:
Breast Cancer, Familial 		0.010 GeneticVariation BEFREE Here, we analysed the influence of the rare c-MYC Asn11Ser polymorphism on familial breast cancer risk by performing a case-control study with a Polish (cases n = 349; controls n = 441) and a German (cases n = 356; controls n = 655) study population. 15929079 2005
dbSNP: rs1057519918
rs1057519918
Entrez Id: 4609;100270680
Gene Symbol: MYC;CASC11
MYC;CASC11
CUI: C0151779
Disease:
Cutaneous Melanoma 		T 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
dbSNP: rs1057519918
rs1057519918
Entrez Id: 4609;100270680
Gene Symbol: MYC;CASC11
MYC;CASC11
CUI: C4721532
Disease:
Lymphoma, Non-Hodgkin, Familial 		T 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
dbSNP: rs1057519918
rs1057519918
Entrez Id: 4609;100270680
Gene Symbol: MYC;CASC11
MYC;CASC11
CUI: C0152013
Disease:
Adenocarcinoma of lung (disorder) 		T 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
dbSNP: rs1057519918
rs1057519918
Entrez Id: 4609;100270680
Gene Symbol: MYC;CASC11
MYC;CASC11
CUI: C2749484
Disease:
NEUROBLASTOMA, SUSCEPTIBILITY TO 		T 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
dbSNP: rs1057519918
rs1057519918
Entrez Id: 4609;100270680
Gene Symbol: MYC;CASC11
MYC;CASC11
CUI: C0152018
Disease:
Esophageal carcinoma 		T 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
dbSNP: rs750664148
rs750664148
Entrez Id: 4609;100270680
Gene Symbol: MYC;CASC11
MYC;CASC11
CUI: C0151779
Disease:
Cutaneous Melanoma 		C 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
dbSNP: rs750664148
rs750664148
Entrez Id: 4609;100270680
Gene Symbol: MYC;CASC11
MYC;CASC11
CUI: C0152013
Disease:
Adenocarcinoma of lung (disorder) 		C 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
dbSNP: rs750664148
rs750664148
Entrez Id: 4609;100270680
Gene Symbol: MYC;CASC11
MYC;CASC11
CUI: C2749484
Disease:
NEUROBLASTOMA, SUSCEPTIBILITY TO 		C 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
dbSNP: rs750664148
rs750664148
Entrez Id: 4609;100270680
Gene Symbol: MYC;CASC11
MYC;CASC11
CUI: C4721532
Disease:
Lymphoma, Non-Hodgkin, Familial 		C 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
dbSNP: rs750664148
rs750664148
Entrez Id: 4609;100270680
Gene Symbol: MYC;CASC11
MYC;CASC11
CUI: C0152018
Disease:
Esophageal carcinoma 		C 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
dbSNP: rs756091827
rs756091827
Entrez Id: 4609;100270680
Gene Symbol: MYC;CASC11
MYC;CASC11
CUI: C2749484
Disease:
NEUROBLASTOMA, SUSCEPTIBILITY TO 		T 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
dbSNP: rs756091827
rs756091827
Entrez Id: 4609;100270680
Gene Symbol: MYC;CASC11
MYC;CASC11
CUI: C0152013
Disease:
Adenocarcinoma of lung (disorder) 		T 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
dbSNP: rs756091827
rs756091827
Entrez Id: 4609;100270680
Gene Symbol: MYC;CASC11
MYC;CASC11
CUI: C0152018
Disease:
Esophageal carcinoma 		T 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
dbSNP: rs756091827
rs756091827
Entrez Id: 4609;100270680
Gene Symbol: MYC;CASC11
MYC;CASC11
CUI: C0151779
Disease:
Cutaneous Melanoma 		T 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
dbSNP: rs756091827
rs756091827
Entrez Id: 4609;100270680
Gene Symbol: MYC;CASC11
MYC;CASC11
CUI: C4721532
Disease:
Lymphoma, Non-Hodgkin, Familial 		T 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
dbSNP: rs4645948
rs4645948
Entrez Id: 4609;100270680
Gene Symbol: MYC;CASC11
MYC;CASC11
CUI: C0002871
Disease:
Anemia 		0.010 GeneticVariation BEFREE In addition, rs4645948 (C>T) was conferred with increased risk of anemia (CT <i>vs</i> CC, OR=2.152, P=0.001) and severe leukopenia (CT <i>vs</i> CC, OR=1.893, P=0.034) for NPC patients receiving chemoradiotherapy. 30662535 2019