NOS3, nitric oxide synthase 3, 4846

N. diseases: 706; N. variants: 39
Disease: Heart failure ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1799983
rs1799983
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C0018801
Disease:
Heart failure 		0.060 GeneticVariation BEFREE Heart failure and endothelial nitric oxide synthase G894T gene polymorphism frequency variations within ancestries. 28554876 2018
dbSNP: rs1799983
rs1799983
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C0018801
Disease:
Heart failure 		0.060 GeneticVariation BEFREE Endothelial nitric oxide synthase (eNOS) Glu298Asp single nucleotide polymorphism (SNP) genotype has been associated with a worse phenotype amongst patients with established heart failure and in patients with progression of their renal disease. 25612295 2015
dbSNP: rs1799983
rs1799983
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C0018801
Disease:
Heart failure 		0.060 GeneticVariation BEFREE Homozygosity for the G allele of the eNOS G894T polymorphism was associated with worse survival in systolic HF patients, especially in those treated with nitrates. 25917853 2015
dbSNP: rs1799983
rs1799983
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C0018801
Disease:
Heart failure 		0.060 GeneticVariation BEFREE To evaluate the association between G894T GP and the prognosis of a sample of Brazilian outpatients with heart failure. 23949326 2013
dbSNP: rs1799983
rs1799983
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C0018801
Disease:
Heart failure 		0.060 GeneticVariation BEFREE This prospective study was designed to analyze the impact of three eNOS polymorphisms (T-786C, VNTR4a/b and Glu298Asp) and their haplotypes on the susceptibility and clinical outcomes in HF outpatients with systolic dysfunction. 22290017 2012
dbSNP: rs1799983
rs1799983
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C0018801
Disease:
Heart failure 		0.060 GeneticVariation BEFREE Endothelial nitric oxide synthase Glu298Asp gene polymorphism in a multi-ethnical population with heart failure and controls. 20079452 2010