GPR143, G protein-coupled receptor 143, 4935

N. diseases: 47; N. variants: 29
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs5934683
rs5934683
Entrez Id: 4935
Gene Symbol: GPR143
GPR143
CUI: C0009402
Disease:
Colorectal Carcinoma
0.810 GeneticVariation BEFREE We identified three new CRC risk loci at 6p21 (rs1321311, near CDKN1A; P = 1.14 × 10(-10)), 11q13.4 (rs3824999, intronic to POLD3; P = 3.65 × 10(-10)) and Xp22.2 (rs5934683, near SHROOM2; P = 7.30 × 10(-10)) This brings the number of independent loci associated with CRC risk to 20 and provides further insight into the genetic architecture of inherited susceptibility to CRC. 22634755 2012
dbSNP: rs5934683
rs5934683
Entrez Id: 4935
Gene Symbol: GPR143
GPR143
CUI: C0009402
Disease:
Colorectal Carcinoma
0.810 GeneticVariation GWASCAT We identified three new CRC risk loci at 6p21 (rs1321311, near CDKN1A; P = 1.14 × 10(-10)), 11q13.4 (rs3824999, intronic to POLD3; P = 3.65 × 10(-10)) and Xp22.2 (rs5934683, near SHROOM2; P = 7.30 × 10(-10)) This brings the number of independent loci associated with CRC risk to 20 and provides further insight into the genetic architecture of inherited susceptibility to CRC. 22634755 2012
dbSNP: rs5934683
rs5934683
Entrez Id: 4935
Gene Symbol: GPR143
GPR143
CUI: C0009402
Disease:
Colorectal Carcinoma
0.810 GeneticVariation GWASDB We identified three new CRC risk loci at 6p21 (rs1321311, near CDKN1A; P = 1.14 × 10(-10)), 11q13.4 (rs3824999, intronic to POLD3; P = 3.65 × 10(-10)) and Xp22.2 (rs5934683, near SHROOM2; P = 7.30 × 10(-10)) This brings the number of independent loci associated with CRC risk to 20 and provides further insight into the genetic architecture of inherited susceptibility to CRC. 22634755 2012