BDNF-AS, BDNF antisense RNA, 497258

N. diseases: 77; N. variants: 60
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs12291063
rs12291063
Entrez Id: 627;497258
Gene Symbol: BDNF;BDNF-AS
BDNF;BDNF-AS
CUI: C0028754
Disease:
Obesity
0.010 GeneticVariation BEFREE Binding and transactivation functions are both disrupted by substituting C for T. These findings provide a rationale for BDNF augmentation as a targeted treatment for obesity in individuals who have the rs12291063 CC genotype. 26526993 2015