OXTR, oxytocin receptor, 5021

N. diseases: 144; N. variants: 19
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2254298
rs2254298
Entrez Id: 859;5021
Gene Symbol: CAV3;OXTR
CAV3;OXTR
CUI: C0003469
Disease:
Anxiety Disorders
0.020 GeneticVariation BEFREE It is suggested that polymorphic variation at the oxytocin receptor gene (rs2254298) is associated with sociability, amygdala volume and differential risk for psychiatric conditions including autism, depression and anxiety disorder, depending on the quality of early environmental experiences. 22510359 2012
dbSNP: rs2254298
rs2254298
Entrez Id: 859;5021
Gene Symbol: CAV3;OXTR
CAV3;OXTR
CUI: C0003469
Disease:
Anxiety Disorders
0.020 GeneticVariation BEFREE More specifically, in a sample of 92 Caucasian adolescent girls (9-14 years old), we examined whether adverse parental environment, operationalized as mothers' history of recurrent major depressive disorder, interacts with the rs2254298 SNP on the OXTR gene to predict daughters' symptoms of depression and anxiety. 20708845 2011