SERPINE1, serpin family E member 1, 5054

N. diseases: 770; N. variants: 23
Disease: Polycystic Ovary Syndrome ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs763351020
rs763351020
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
CUI: C0032460
Disease:
Polycystic Ovary Syndrome 		0.030 GeneticVariation BEFREE Meta-analysis showed no association between PCOS and the MTHFR 677C/T polymorphism using homozygote contrast, and recessive and dominant models. 24439532 2014
dbSNP: rs763351020
rs763351020
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
CUI: C0032460
Disease:
Polycystic Ovary Syndrome 		0.030 GeneticVariation BEFREE No evidence was found for association of MTHFR C677T polymorphism with PCOS (OR for the TT+CT versus CC comparison equal to 0.940 with 95% CI 0.561, 1.575). 19066200 2009
dbSNP: rs763351020
rs763351020
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
CUI: C0032460
Disease:
Polycystic Ovary Syndrome 		0.030 GeneticVariation BEFREE Cases (PCOS-RPL, RPL without PCOS) were compared with controls (116 healthy Caucasian females) for the G1691A Factor V Leiden, G20210A prothrombin, C677T methylenetetrahydrofolate reductase (MTHFR), plasminogen activator inhibitor 4G/5G, and platelet glycoprotein PL A1A2 gene mutations. 14669168 2003