SERPINE1, serpin family E member 1, 5054

N. diseases: 770; N. variants: 23
Disease: Metabolic Syndrome X ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1799768
rs1799768
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
CUI: C0524620
Disease:
Metabolic Syndrome X 		0.010 GeneticVariation BEFREE The prevalence of the MetS was 23%.In a marker-by-marker analysis, the ADRB2 rs180088 (OR 1.22, 95% CI 1.01-1.48) and PAI1 r</span>s1799768 (OR 1.05, 95% CI 1.01-1.10) were associated with an increased MetS risk, whereas the C5 rs17611 (OR 0.95, 95% CI 0.91-1.00) and the CTLA4 rs5742909 (OR 0.91, 95% CI 0.84-0.99) were associated with a decreased risk. 19619703 2009