SERPINE1, serpin family E member 1, 5054

N. diseases: 770; N. variants: 23
Disease: Coronary Artery Disease ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2227631
rs2227631
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
CUI: C1956346
Disease:
Coronary Artery Disease 		0.010 GeneticVariation BEFREE Further subgroup analyses based on type of disease and ethnicity of participants suggested that the rs2227631 polymorphism was significantly associated with the risk of coronary artery disease in the dominant (95% CI 0.71-0.94) and allele (95% CI 0.80-0.94) models, whereas the rs1799889 polymorphism was significantly associated with the risk of myocardial infarction (dominant model: 95% CI 1.09-1.57; recessive model: 95% CI 0.71-0.96; allele model: 95% CI 1.05-1.28) and cerebral infarction (dominant model: 95% CI 1.68-3.51; additive model: 95% CI 0.39-0.77; allele model: 95% CI 1.23-2.00). 29908999 2018