rs1057517661
|
GAL;LOC107984343
|
EPILEPSY, FAMILIAL TEMPORAL LOBE, 8
|
|
0.700 |
GeneticVariation |
UNIPROT |
|
|
|
rs948854
|
GAL;LOC107984343
|
Depressive Symptoms
|
|
0.020 |
GeneticVariation |
BEFREE |
Furthermore, rs948854 minor (G) allele was associated with depressive symptoms.
|
28987550 |
2018 |
rs948854
|
GAL;LOC107984343
|
Depressive Symptoms
|
|
0.020 |
GeneticVariation |
BEFREE |
In premenopausal female MDD patients, the same allele of rs948854 was associated with more severe vegetative but not cognitive depressive symptoms at discharge and worse treatment response on antidepressant medication.
|
20237460 |
2010 |
rs948854
|
GAL;LOC107984343
|
Mental Depression
|
|
0.010 |
GeneticVariation |
BEFREE |
In conclusion, the SNP rs948854 in the GAL gene seems to be involved in the modulation of depressive state, especially in individuals with GG genotype.
|
28987550 |
2018 |
rs948854
|
GAL;LOC107984343
|
Multiple Sclerosis
|
|
0.010 |
GeneticVariation |
BEFREE |
These data demonstrate for the first time an association between rs948854 polymorphism and multiple sclerosis and, further, that this association is sex specific.
|
27870457 |
2017 |
rs1057517661
|
GAL;LOC107984343
|
Epilepsy, Temporal Lobe
|
|
0.010 |
GeneticVariation |
BEFREE |
These findings suggest that the p.A39E mutant could impair galanin signaling in the hippocampus, leading to increased glutamatergic excitation and ultimately to TLE.
|
25691535 |
2015 |
rs694066
|
GAL;LOC107984343
|
Major Depressive Disorder
|
|
0.010 |
GeneticVariation |
BEFREE |
Compared with the healthy controls, lower frequency of G/G genotype and higher frequency of A/G genotype were observed in rs694066 in MDD patients, a lower frequency of G-allele and higher frequency of A-allele were observed in rs694066.
|
23741354 |
2013 |
rs948854
|
GAL;LOC107984343
|
Opiate Addiction
|
|
0.010 |
GeneticVariation |
BEFREE |
The most significant associations with opioid addiction (remaining significant after adjustment for multiple testing) were observed for the rs948854 SNP in the galanin gene (GAL, p = 0.001) and the rs2236861 SNP in the delta opioid receptor gene (OPRD1, p = 0.001).
|
24086514 |
2013 |