WNT16, Wnt family member 16, 51384

N. diseases: 29; N. variants: 7
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs3779381
rs3779381
Entrez Id: 51384
Gene Symbol: WNT16
WNT16
CUI: C0349782
Disease:
Ischemic cardiomyopathy
G 0.700 GeneticVariation GWASCAT Identification of a 3'-Untranslated Genetic Variant of RARB Associated With Carotid Intima-Media Thickness in Rheumatoid Arthritis: A Genome-Wide Association Study. 30251476 2019
dbSNP: rs3779381
rs3779381
Entrez Id: 51384
Gene Symbol: WNT16
WNT16
CUI: C0003873
Disease:
Rheumatoid Arthritis
G 0.700 GeneticVariation GWASCAT Identification of a 3'-Untranslated Genetic Variant of RARB Associated With Carotid Intima-Media Thickness in Rheumatoid Arthritis: A Genome-Wide Association Study. 30251476 2019
dbSNP: rs3801387
rs3801387
Entrez Id: 51384
Gene Symbol: WNT16
WNT16
CUI: C0005938
Disease:
Bone Density
A 0.700 GeneticVariation GWASCAT Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects. 29304378 2018
dbSNP: rs2908004
rs2908004
Entrez Id: 51384
Gene Symbol: WNT16
WNT16
CUI: C0005938
Disease:
Bone Density
A 0.700 GeneticVariation GWASCAT Phenotypic dissection of bone mineral density reveals skeletal site specificity and facilitates the identification of novel loci in the genetic regulation of bone mass attainment. 24945404 2014
dbSNP: rs3801387
rs3801387
Entrez Id: 51384
Gene Symbol: WNT16
WNT16
CUI: C0177804
Disease:
Bone Mineral Density Test
0.700 GeneticVariation GWASDB Multistage genome-wide association meta-analyses identified two new loci for bone mineral density. 24249740 2014
dbSNP: rs2536189
rs2536189
Entrez Id: 51384
Gene Symbol: WNT16
WNT16
CUI: C0177804
Disease:
Bone Mineral Density Test
0.700 GeneticVariation GWASDB Meta-analysis of genome-wide scans for total body BMD in children and adults reveals allelic heterogeneity and age-specific effects at the WNT16 locus. 22792070 2012
dbSNP: rs2707466
rs2707466
Entrez Id: 51384
Gene Symbol: WNT16
WNT16
CUI: C0177804
Disease:
Bone Mineral Density Test
0.700 GeneticVariation GWASDB Meta-analysis of genome-wide scans for total body BMD in children and adults reveals allelic heterogeneity and age-specific effects at the WNT16 locus. 22792070 2012
dbSNP: rs2908004
rs2908004
Entrez Id: 51384
Gene Symbol: WNT16
WNT16
CUI: C0177804
Disease:
Bone Mineral Density Test
G 0.700 GeneticVariation GWASDB WNT16 influences bone mineral density, cortical bone thickness, bone strength, and osteoporotic fracture risk. 22792071 2012
dbSNP: rs2908004
rs2908004
Entrez Id: 51384
Gene Symbol: WNT16
WNT16
CUI: C0177804
Disease:
Bone Mineral Density Test
0.700 GeneticVariation GWASDB Meta-analysis of genome-wide scans for total body BMD in children and adults reveals allelic heterogeneity and age-specific effects at the WNT16 locus. 22792070 2012
dbSNP: rs2908004
rs2908004
Entrez Id: 51384
Gene Symbol: WNT16
WNT16
CUI: C0005938
Disease:
Bone Density
G 0.700 GeneticVariation GWASCAT WNT16 influences bone mineral density, cortical bone thickness, bone strength, and osteoporotic fracture risk. 22792071 2012
dbSNP: rs3757552
rs3757552
Entrez Id: 51384
Gene Symbol: WNT16
WNT16
CUI: C0177804
Disease:
Bone Mineral Density Test
0.700 GeneticVariation GWASDB Meta-analysis of genome-wide scans for total body BMD in children and adults reveals allelic heterogeneity and age-specific effects at the WNT16 locus. 22792070 2012
dbSNP: rs3779381
rs3779381
Entrez Id: 51384
Gene Symbol: WNT16
WNT16
CUI: C0177804
Disease:
Bone Mineral Density Test
0.700 GeneticVariation GWASDB Meta-analysis of genome-wide scans for total body BMD in children and adults reveals allelic heterogeneity and age-specific effects at the WNT16 locus. 22792070 2012
dbSNP: rs3801385
rs3801385
Entrez Id: 51384
Gene Symbol: WNT16
WNT16
CUI: C0177804
Disease:
Bone Mineral Density Test
0.700 GeneticVariation GWASDB Meta-analysis of genome-wide scans for total body BMD in children and adults reveals allelic heterogeneity and age-specific effects at the WNT16 locus. 22792070 2012
dbSNP: rs3801387
rs3801387
Entrez Id: 51384
Gene Symbol: WNT16
WNT16
CUI: C0177804
Disease:
Bone Mineral Density Test
A 0.700 GeneticVariation GWASDB Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. 22504420 2012
dbSNP: rs3801387
rs3801387
Entrez Id: 51384
Gene Symbol: WNT16
WNT16
CUI: C0177804
Disease:
Bone Mineral Density Test
0.700 GeneticVariation GWASDB Meta-analysis of genome-wide scans for total body BMD in children and adults reveals allelic heterogeneity and age-specific effects at the WNT16 locus. 22792070 2012
dbSNP: rs3801387
rs3801387
Entrez Id: 51384
Gene Symbol: WNT16
WNT16
CUI: C0005938
Disease:
Bone Density
A 0.700 GeneticVariation GWASCAT Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. 22504420 2012
dbSNP: rs2908004
rs2908004
Entrez Id: 51384
Gene Symbol: WNT16
WNT16
CUI: C0029408
Disease:
Degenerative polyarthritis
0.010 GeneticVariation BEFREE In conclusion, two SNPs (rs2908004 and rs1799986) are associated with the decreased risk of OA by regulating the Wnt pathway. 31560818 2019
dbSNP: rs2908004
rs2908004
Entrez Id: 51384
Gene Symbol: WNT16
WNT16
CUI: C0521170
Disease:
Osteoporotic Fractures
0.010 GeneticVariation BEFREE The main finding was that of significant differences in the polymorphisms of the WNT16 rs2908004 genetic variant, notably, the less frequent presence of TC allele in women with a greater risk of osteoporotic fractures. 31309515 2019
dbSNP: rs2707466
rs2707466
Entrez Id: 51384
Gene Symbol: WNT16
WNT16
CUI: C0029410
Disease:
Osteoarthritis of hip
0.010 GeneticVariation BEFREE Thus, there was a significant difference in the genotypic frequencies of rs2707466 between hypertrophic and atrophic hip OA in males (p = 0.003), with overrepresentation of G alleles in the hypertrophic phenotype (OR 2.08; CI 1.28-3.38). 28766055 2017