REV1, REV1 DNA directed polymerase, 51455

N. diseases: 28; N. variants: 15
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs3792142
rs3792142
Entrez Id: 51455
Gene Symbol: REV1
REV1
CUI: C0596887
Disease:
mathematical ability 		A 0.700 GeneticVariation GWASCAT Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals. 30038396 2018
dbSNP: rs6761390
rs6761390
Entrez Id: 51455
Gene Symbol: REV1
REV1
CUI: C0596887
Disease:
mathematical ability 		C 0.700 GeneticVariation GWASCAT Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals. 30038396 2018
dbSNP: rs1011633
rs1011633
Entrez Id: 51455
Gene Symbol: REV1
REV1
CUI: C1269683
Disease:
Major Depressive Disorder 		0.700 GeneticVariation GWASDB A mega-analysis of genome-wide association studies for major depressive disorder. 22472876 2013
dbSNP: rs1053544
rs1053544
Entrez Id: 51455
Gene Symbol: REV1
REV1
CUI: C1269683
Disease:
Major Depressive Disorder 		0.700 GeneticVariation GWASDB A mega-analysis of genome-wide association studies for major depressive disorder. 22472876 2013
dbSNP: rs11899745
rs11899745
Entrez Id: 51455
Gene Symbol: REV1
REV1
CUI: C1269683
Disease:
Major Depressive Disorder 		0.700 GeneticVariation GWASDB A mega-analysis of genome-wide association studies for major depressive disorder. 22472876 2013
dbSNP: rs2290261
rs2290261
Entrez Id: 51455
Gene Symbol: REV1
REV1
CUI: C1269683
Disease:
Major Depressive Disorder 		0.700 GeneticVariation GWASDB A mega-analysis of genome-wide association studies for major depressive disorder. 22472876 2013
dbSNP: rs3792137
rs3792137
Entrez Id: 51455
Gene Symbol: REV1
REV1
CUI: C1269683
Disease:
Major Depressive Disorder 		0.700 GeneticVariation GWASDB A mega-analysis of genome-wide association studies for major depressive disorder. 22472876 2013
dbSNP: rs4851206
rs4851206
Entrez Id: 51455
Gene Symbol: REV1
REV1
CUI: C1269683
Disease:
Major Depressive Disorder 		0.700 GeneticVariation GWASDB A mega-analysis of genome-wide association studies for major depressive disorder. 22472876 2013
dbSNP: rs717454
rs717454
Entrez Id: 51455
Gene Symbol: REV1
REV1
CUI: C1269683
Disease:
Major Depressive Disorder 		0.700 GeneticVariation GWASDB A mega-analysis of genome-wide association studies for major depressive disorder. 22472876 2013
dbSNP: rs7585019
rs7585019
Entrez Id: 51455
Gene Symbol: REV1
REV1
CUI: C1269683
Disease:
Major Depressive Disorder 		0.700 GeneticVariation GWASDB A mega-analysis of genome-wide association studies for major depressive disorder. 22472876 2013
dbSNP: rs769105
rs769105
Entrez Id: 51455
Gene Symbol: REV1
REV1
CUI: C1269683
Disease:
Major Depressive Disorder 		0.700 GeneticVariation GWASDB A mega-analysis of genome-wide association studies for major depressive disorder. 22472876 2013
dbSNP: rs717454
rs717454
Entrez Id: 51455
Gene Symbol: REV1
REV1
CUI: C0525045
Disease:
Mood Disorders 		0.010 GeneticVariation BEFREE When combining all samples, this SNP and multiple other SNPs at 2q11.2 (rs717454), 8q21.3 (rs10103191), and 11q13.2 (rs2167457) exhibited genome-wide significant association with major mood disorders. 29225345 2017
dbSNP: rs3087403
rs3087403
Entrez Id: 51455
Gene Symbol: REV1
REV1
CUI: C0027947
Disease:
Neutropenia 		0.010 GeneticVariation BEFREE Polymorphic REV1 rs3087403 allele and REV1 TGT haplotype were associated with increased risk for leukopenia (p = 0.013 and p = 0.047, respectively) and neutropenia (p = 0.048 and p = 0.024, respectively). 24956248 2014
dbSNP: rs3087403
rs3087403
Entrez Id: 51455
Gene Symbol: REV1
REV1
CUI: C0023530
Disease:
Leukopenia 		0.010 GeneticVariation BEFREE Polymorphic REV1 rs3087403 allele and REV1 TGT haplotype were associated with increased risk for leukopenia (p = 0.013 and p = 0.047, respectively) and neutropenia (p = 0.048 and p = 0.024, respectively). 24956248 2014
dbSNP: rs3087386
rs3087386
Entrez Id: 51455
Gene Symbol: REV1
REV1
CUI: C1306460
Disease:
Primary malignant neoplasm of lung 		0.010 GeneticVariation BEFREE Besides, the heterozygote of REV1 rs3087386 and rs3792136 were independent prognostic factors for lung cancer survival with hazard radio (HR) 1.54 (95% CI: 1.12-2.12) and 1.44 (95% CI: 1.06-1.97) respectively. 24012694 2013
dbSNP: rs3087386
rs3087386
Entrez Id: 51455
Gene Symbol: REV1
REV1
CUI: C0242379
Disease:
Malignant neoplasm of lung 		0.010 GeneticVariation BEFREE Besides, the heterozygote of REV1 rs3087386 and rs3792136 were independent prognostic factors for lung cancer survival with hazard radio (HR) 1.54 (95% CI: 1.12-2.12) and 1.44 (95% CI: 1.06-1.97) respectively. 24012694 2013
dbSNP: rs3087386
rs3087386
Entrez Id: 51455
Gene Symbol: REV1
REV1
CUI: C0684249
Disease:
Carcinoma of lung 		0.010 GeneticVariation BEFREE Besides, the heterozygote of REV1 rs3087386 and rs3792136 were independent prognostic factors for lung cancer survival with hazard radio (HR) 1.54 (95% CI: 1.12-2.12) and 1.44 (95% CI: 1.06-1.97) respectively. 24012694 2013
dbSNP: rs3792136
rs3792136
Entrez Id: 51455
Gene Symbol: REV1
REV1
CUI: C0684249
Disease:
Carcinoma of lung 		0.010 GeneticVariation BEFREE Besides, the heterozygote of REV1 rs3087386 and rs3792136 were independent prognostic factors for lung cancer survival with hazard radio (HR) 1.54 (95% CI: 1.12-2.12) and 1.44 (95% CI: 1.06-1.97) respectively. 24012694 2013
dbSNP: rs3792136
rs3792136
Entrez Id: 51455
Gene Symbol: REV1
REV1
CUI: C1306460
Disease:
Primary malignant neoplasm of lung 		0.010 GeneticVariation BEFREE Besides, the heterozygote of REV1 rs3087386 and rs3792136 were independent prognostic factors for lung cancer survival with hazard radio (HR) 1.54 (95% CI: 1.12-2.12) and 1.44 (95% CI: 1.06-1.97) respectively. 24012694 2013
dbSNP: rs3792136
rs3792136
Entrez Id: 51455
Gene Symbol: REV1
REV1
CUI: C0242379
Disease:
Malignant neoplasm of lung 		0.010 GeneticVariation BEFREE Besides, the heterozygote of REV1 rs3087386 and rs3792136 were independent prognostic factors for lung cancer survival with hazard radio (HR) 1.54 (95% CI: 1.12-2.12) and 1.44 (95% CI: 1.06-1.97) respectively. 24012694 2013
dbSNP: rs3792142
rs3792142
Entrez Id: 51455
Gene Symbol: REV1
REV1
CUI: C0027651
Disease:
Neoplasms 		0.010 GeneticVariation BEFREE Minor allele carriers of two REV1 SNPs (rs6761391 and rs3792142) had significantly more often large tumours and tumours with high histological grade and stage. 21455670 2011
dbSNP: rs3087386
rs3087386
Entrez Id: 51455
Gene Symbol: REV1
REV1
CUI: C0007137
Disease:
Squamous cell carcinoma 		0.010 GeneticVariation BEFREE In addition, we found that the association of Phe257Ser and Asn373Ser with the risk for cervical carcinoma was specific to squamous cell carcinomas and not relevant for adenocarcinoma. 18470628 2008
dbSNP: rs3087386
rs3087386
Entrez Id: 51455
Gene Symbol: REV1
REV1
CUI: C0279671
Disease:
Cervical Squamous Cell Carcinoma 		0.010 GeneticVariation BEFREE Compared with the REV1 Phe257Ser, women carrying Ser257Ser and Phe257Ser genotypes had a significantly decreased the risk for cervical carcinoma or cervical squamous cell carcinoma. 18470628 2008
dbSNP: rs3087386
rs3087386
Entrez Id: 51455
Gene Symbol: REV1
REV1
CUI: C0343641
Disease:
Human papilloma virus infection 		0.010 GeneticVariation BEFREE Two single nucleotide polymorphisms (SNPs) (REV1 Phe257Ser and REV1 Asn373Ser) were genotyped by PCR-squencing, and analysis the correlation to clinical character including HPV infection. 18470628 2008
dbSNP: rs3087386
rs3087386
Entrez Id: 51455
Gene Symbol: REV1
REV1
CUI: C0001418
Disease:
Adenocarcinoma 		0.010 GeneticVariation BEFREE In addition, we found that the association of Phe257Ser and Asn373Ser with the risk for cervical carcinoma was specific to squamous cell carcinomas and not relevant for adenocarcinoma. 18470628 2008