SERPINF1, serpin family F member 1, 5176

N. diseases: 294; N. variants: 15
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1418184396
rs1418184396
Entrez Id: 5176
Gene Symbol: SERPINF1
SERPINF1
CUI: C0162871
Disease:
Aortic Aneurysm, Abdominal 		0.010 GeneticVariation BEFREE The TAFI Thr325Ile and the tPA 7351C→T polymorphisms were not associated with AAA. 25065555 2014
dbSNP: rs1136287
rs1136287
Entrez Id: 5176
Gene Symbol: SERPINF1
SERPINF1
CUI: C0242383
Disease:
Age related macular degeneration 		0.060 GeneticVariation BEFREE There was evidence to suggest that heterozygotes for rs1136287 (C/T) exerted a protective effect against exudative AMD (additive model, OR 0.59, CI 0.36-0.95, p = 0.03), but none of the p-values in the other genotype groups were statistically significant. 21174599 2011
dbSNP: rs1136287
rs1136287
Entrez Id: 5176
Gene Symbol: SERPINF1
SERPINF1
CUI: C0017921
Disease:
Glycogen storage disease type II 		0.020 GeneticVariation BEFREE There was evidence to suggest that heterozygotes for rs1136287 (C/T) exerted a protective effect against exudative AMD (additive model, OR 0.59, CI 0.36-0.95, p = 0.03), but none of the p-values in the other genotype groups were statistically significant. 21174599 2011
dbSNP: rs1136287
rs1136287
Entrez Id: 5176
Gene Symbol: SERPINF1
SERPINF1
CUI: C0028754
Disease:
Obesity 		0.010 GeneticVariation BEFREE We analyzed the polymorphisms rs846910, rs1205, rs1501299, rs1801282, rs1800497, rs757110 and rs1136287 in these candidate genes, for association with obesity and metabolic traits in a young Mexican-American population from south Texas. 22056417 2011
dbSNP: rs12603825
rs12603825
Entrez Id: 5176
Gene Symbol: SERPINF1
SERPINF1
CUI: C0027092
Disease:
Myopia 		0.010 GeneticVariation BEFREE We demonstrated a marginal association of the PEDF SNP, rs12603825, with myopic CNV in extremely myopic patients. 23722394 2013
dbSNP: rs1136287
rs1136287
Entrez Id: 5176
Gene Symbol: SERPINF1
SERPINF1
CUI: C0242383
Disease:
Age related macular degeneration 		0.060 GeneticVariation BEFREE We report a lack of association between the PEDF Met72Thr variant and either neovascular AMD or PCV in a Japanese population. 19503741 2009
dbSNP: rs1136287
rs1136287
Entrez Id: 5176
Gene Symbol: SERPINF1
SERPINF1
CUI: C0017921
Disease:
Glycogen storage disease type II 		0.020 GeneticVariation BEFREE We report a lack of association between the PEDF Met72Thr variant and either neovascular AMD or PCV in a Japanese population. 19503741 2009
dbSNP: rs1136287
rs1136287
Entrez Id: 5176
Gene Symbol: SERPINF1
SERPINF1
CUI: C1504336
Disease:
Polypoidal choroidal vasculopathy 		0.020 GeneticVariation BEFREE We report a lack of association between the PEDF Met72Thr variant and either neovascular AMD or PCV in a Japanese population. 19503741 2009