Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs752021744
rs752021744
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB
CUI: C0027627
Disease:
Neoplasm Metastasis
0.020 GeneticVariation BEFREE GTPase-impairing somatic mutations in RAS genes, such as KRAS(G12D), are among the most common oncogenic events in metastatic cancer. 26549032 2016
dbSNP: rs752021744
rs752021744
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB
CUI: C0027627
Disease:
Neoplasm Metastasis
0.020 GeneticVariation BEFREE In mice, Lkb1 deletion and activation of Kras(G12D) results in lung tumors with a high penetrance of lymph node and distant metastases. 20541700 2010