DisGeNET - a database of gene-disease associations

PIK3CG, phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma, 5294

N. diseases: 1101; N. variants: 12

Disease: Malignant Neoplasms ×

Variant: rs1226994105 ×

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Disease

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs1226994105

Entrez Id:	5294
Gene Symbol:	PIK3CG

PIK3CG

CUI:	C0006826
Disease:

Malignant Neoplasms

0.010

GeneticVariation

BEFREE

These findings open the possibility that blocking of PI3K/AKT will have therapeutic benefit in mutant p53-R273H expressing cancers.

26181206

2015