rs587779345
×
Entrez Id:
5395
Gene Symbol:
PMS2
PMS2
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 4
0.700
GeneticVariation
UNIPROT
Recommendations for reporting of secondary findings in clinical exome and genome sequencing, 2016 update (ACMG SF v2.0): a policy statement of the American College of Medical Genetics and Genomics.
27854360
2017
rs587779345
×
Entrez Id:
5395
Gene Symbol:
PMS2
PMS2
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 4
0.700
GeneticVariation
UNIPROT
ACMG policy statement: updated recommendations regarding analysis and reporting of secondary findings in clinical genome-scale sequencing.
25356965
2015
rs587779345
×
Entrez Id:
5395
Gene Symbol:
PMS2
PMS2
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 4
0.700
GeneticVariation
UNIPROT
ACMG recommendations for reporting of incidental findings in clinical exome and genome sequencing.
23788249
2013
rs587779345
×
Entrez Id:
5395
Gene Symbol:
PMS2
PMS2
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 4
0.700
GeneticVariation
UNIPROT
Refining the role of PMS2 in Lynch syndrome: germline mutational analysis improved by comprehensive assessment of variants.
23709753
2013
rs587779345
×
Entrez Id:
5395
Gene Symbol:
PMS2
PMS2
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 4
0.700
GeneticVariation
UNIPROT
Inactivation of DNA mismatch repair by variants of uncertain significance in the PMS2 gene.
24027009
2013
rs587779345
×
Entrez Id:
5395
Gene Symbol:
PMS2
PMS2
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 4
0.700
GeneticVariation
UNIPROT
Four novel germline mutations in the MLH1 and PMS2 mismatch repair genes in patients with hereditary nonpolyposis colorectal cancer.
19479271
2009
rs587779345
×
Entrez Id:
5395
Gene Symbol:
PMS2
PMS2
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 4
0.700
GeneticVariation
UNIPROT
The clinical phenotype of Lynch syndrome due to germ-line PMS2 mutations.
18602922
2008
rs587779345
×
Entrez Id:
5395
Gene Symbol:
PMS2
PMS2
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 4
0.700
GeneticVariation
UNIPROT
A frame-shift mutation of PMS2 is a widespread cause of Lynch syndrome.
18178629
2008
rs587779345
×
Entrez Id:
5395
Gene Symbol:
PMS2
PMS2
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 4
0.700
GeneticVariation
UNIPROT
Heterozygous mutations in PMS2 cause hereditary nonpolyposis colorectal carcinoma (Lynch syndrome).
16472587
2006
rs587779345
×
Entrez Id:
5395
Gene Symbol:
PMS2
PMS2
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 4
0.700
GeneticVariation
UNIPROT
Long-range PCR facilitates the identification of PMS2-specific mutations.
16619239
2006
rs587779345
×
Entrez Id:
5395
Gene Symbol:
PMS2
PMS2
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 4
0.700
GeneticVariation
UNIPROT
Familial mutations in PMS2 can cause autosomal dominant hereditary nonpolyposis colorectal cancer.
15887124
2005
rs587779345
×
Entrez Id:
5395
Gene Symbol:
PMS2
PMS2
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 4
0.700
GeneticVariation
UNIPROT
Polymorphisms and HNPCC: PMS2-MLH1 protein interactions diminished by single nucleotide polymorphisms.
11793469
2002
rs587779345
×
Entrez Id:
5395
Gene Symbol:
PMS2
PMS2
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 4
0.700
GeneticVariation
UNIPROT
Prevalence of germline mutations of hMLH1, hMSH2, hPMS1, hPMS2, and hMSH6 genes in 75 French kindreds with nonpolyposis colorectal cancer.
10480359
1999