TLR9, toll like receptor 9, 54106

N. diseases: 457; N. variants: 11
Disease: Tuberculosis, Pulmonary ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs187084
rs187084
Entrez Id: 54106
Gene Symbol: TLR9
TLR9
CUI: C0041327
Disease:
Tuberculosis, Pulmonary 		0.030 GeneticVariation BEFREE The G allele of TLR9 SNP rs187084 was found to increase the risk of PTB (G vs A, P = 0.01, OR = 1.48, 95% CI = 1.10-2.00), the significance was also observed under dominant genetic models. 30424735 2018
dbSNP: rs187084
rs187084
Entrez Id: 54106
Gene Symbol: TLR9
TLR9
CUI: C0041327
Disease:
Tuberculosis, Pulmonary 		0.030 GeneticVariation BEFREE BACKGROUND Findings regarding the association of the single-nucleotide polymorphisms (SNPs) rs4986790 and rs4986791 in Toll-like receptor 4 and rs187084, rs574386, and rs352139 in Toll-like receptor 9 (TLR9) with pulmonary tuberculosis (PTB) susceptibility are inconsistent. 25889916 2015
dbSNP: rs187084
rs187084
Entrez Id: 54106
Gene Symbol: TLR9
TLR9
CUI: C0041327
Disease:
Tuberculosis, Pulmonary 		0.030 GeneticVariation BEFREE Collectively, these data suggest that the minor "C" allele at rs187084 locus may be associated with susceptibility to PTB, which may explain the relatively lower PTB rates observed in Baiga tribe members. 25248338 2014