WNT4, Wnt family member 4, 54361

N. diseases: 135; N. variants: 14
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2235529
rs2235529
Entrez Id: 54361
Gene Symbol: WNT4
WNT4
CUI: C0014175
Disease:
Endometriosis 		0.820 GeneticVariation BEFREE This might constitute the first step towards identifying polymorphism combinations that predispose to endometriosis (IFNG (CA) repeat, GSTM1 null genotype, GSTP1 rs1695, WNT4 rs16826658 and WNT4 rs2235529) in a large cohort of patients with well-defined inclusion criteria. 31821471 2020
dbSNP: rs2235529
rs2235529
Entrez Id: 54361
Gene Symbol: WNT4
WNT4
CUI: C0014175
Disease:
Endometriosis 		0.820 GeneticVariation BEFREE The results demonstrated that WNT4 rs2235529 is associated with endometriosis in Chinese Han women, which may result in aberrant expression of WNT4, leading to the pathogenesis of endometriosis. 25682310 2015
dbSNP: rs2235529
rs2235529
Entrez Id: 54361
Gene Symbol: WNT4
WNT4
CUI: C0014175
Disease:
Endometriosis 		A 0.820 GeneticVariation GWASDB Genome-wide association study link novel loci to endometriosis. 23472165 2013
dbSNP: rs2235529
rs2235529
Entrez Id: 54361
Gene Symbol: WNT4
WNT4
CUI: C0014175
Disease:
Endometriosis 		T 0.820 GeneticVariation GWASCAT Genome-wide association study link novel loci to endometriosis. 23472165 2013
dbSNP: rs2235529
rs2235529
Entrez Id: 54361
Gene Symbol: WNT4
WNT4
CUI: C0014175
Disease:
Endometriosis 		A 0.820 GeneticVariation GWASCAT Genome-wide association study link novel loci to endometriosis. 23472165 2013
dbSNP: rs121908650
rs121908650
Entrez Id: 54361
Gene Symbol: WNT4
WNT4
CUI: C2675014
Disease:
Mullerian Aplasia and Hyperandrogenism 		0.800 GeneticVariation UNIPROT Identification and functional analysis of a new WNT4 gene mutation among 28 adolescent girls with primary amenorrhea and müllerian duct abnormalities: a French collaborative study. 18182450 2008
dbSNP: rs121908653
rs121908653
Entrez Id: 54361;105376845
Gene Symbol: WNT4;LOC105376845
WNT4;LOC105376845
CUI: C2675014
Disease:
Mullerian Aplasia and Hyperandrogenism 		0.800 GeneticVariation UNIPROT Identification and functional analysis of a new WNT4 gene mutation among 28 adolescent girls with primary amenorrhea and müllerian duct abnormalities: a French collaborative study. 18182450 2008
dbSNP: rs121908650
rs121908650
Entrez Id: 54361
Gene Symbol: WNT4
WNT4
CUI: C2675014
Disease:
Mullerian Aplasia and Hyperandrogenism 		0.800 GeneticVariation UNIPROT WNT4 deficiency--a clinical phenotype distinct from the classic Mayer-Rokitansky-Kuster-Hauser syndrome: a case report. 16959810 2007
dbSNP: rs121908653
rs121908653
Entrez Id: 54361;105376845
Gene Symbol: WNT4;LOC105376845
WNT4;LOC105376845
CUI: C2675014
Disease:
Mullerian Aplasia and Hyperandrogenism 		0.800 GeneticVariation UNIPROT WNT4 deficiency--a clinical phenotype distinct from the classic Mayer-Rokitansky-Kuster-Hauser syndrome: a case report. 16959810 2007
dbSNP: rs121908650
rs121908650
Entrez Id: 54361
Gene Symbol: WNT4
WNT4
CUI: C2675014
Disease:
Mullerian Aplasia and Hyperandrogenism 		0.800 GeneticVariation UNIPROT A WNT4 mutation associated with Müllerian-duct regression and virilization in a 46,XX woman. 15317892 2004
dbSNP: rs121908653
rs121908653
Entrez Id: 54361;105376845
Gene Symbol: WNT4;LOC105376845
WNT4;LOC105376845
CUI: C2675014
Disease:
Mullerian Aplasia and Hyperandrogenism 		0.800 GeneticVariation UNIPROT A WNT4 mutation associated with Müllerian-duct regression and virilization in a 46,XX woman. 15317892 2004
dbSNP: rs121908650
rs121908650
Entrez Id: 54361
Gene Symbol: WNT4
WNT4
CUI: C2675014
Disease:
Mullerian Aplasia and Hyperandrogenism 		C 0.800 CausalMutation CLINVAR
dbSNP: rs121908653
rs121908653
Entrez Id: 54361;105376845
Gene Symbol: WNT4;LOC105376845
WNT4;LOC105376845
CUI: C2675014
Disease:
Mullerian Aplasia and Hyperandrogenism 		G 0.800 CausalMutation CLINVAR
dbSNP: rs12404660
rs12404660
Entrez Id: 54361
Gene Symbol: WNT4
WNT4
CUI: C0205682
Disease:
Waist-Hip Ratio 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs7526484
rs7526484
Entrez Id: 54361
Gene Symbol: WNT4
WNT4
CUI: C0021704
Disease:
Intelligence 		T 0.700 GeneticVariation GWASCAT Biological annotation of genetic loci associated with intelligence in a meta-analysis of 87,740 individuals. 29520040 2019
dbSNP: rs10737462
rs10737462
Entrez Id: 54361
Gene Symbol: WNT4
WNT4
CUI: C0005938
Disease:
Bone Density 		T 0.700 GeneticVariation GWASCAT Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects. 29304378 2018
dbSNP: rs12037376
rs12037376
Entrez Id: 54361
Gene Symbol: WNT4
WNT4
CUI: C2242776
Disease:
Plexiform leiomyoma 		A 0.700 GeneticVariation GWASCAT Variants associating with uterine leiomyoma highlight genetic background shared by various cancers and hormone-related traits. 30194396 2018
dbSNP: rs12037376
rs12037376
Entrez Id: 54361
Gene Symbol: WNT4
WNT4
CUI: C0042133
Disease:
Uterine Fibroids 		A 0.700 GeneticVariation GWASCAT Variants associating with uterine leiomyoma highlight genetic background shared by various cancers and hormone-related traits. 30194396 2018
dbSNP: rs2235529
rs2235529
Entrez Id: 54361
Gene Symbol: WNT4
WNT4
CUI: C0205682
Disease:
Waist-Hip Ratio 		C 0.700 GeneticVariation GWASCAT Association of Genetic Variants Related to Gluteofemoral vs Abdominal Fat Distribution With Type 2 Diabetes, Coronary Disease, and Cardiovascular Risk Factors. 30575882 2018
dbSNP: rs56318008
rs56318008
Entrez Id: 54361;105376845
Gene Symbol: WNT4;LOC105376845
WNT4;LOC105376845
CUI: C0005938
Disease:
Bone Density 		T 0.700 GeneticVariation GWASCAT Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects. 29304378 2018
dbSNP: rs12037376
rs12037376
Entrez Id: 54361
Gene Symbol: WNT4
WNT4
CUI: C0014175
Disease:
Endometriosis 		A 0.700 GeneticVariation GWASCAT Meta-analysis identifies five novel loci associated with endometriosis highlighting key genes involved in hormone metabolism. 28537267 2017
dbSNP: rs3765350
rs3765350
Entrez Id: 54361
Gene Symbol: WNT4
WNT4
CUI: C0424678
Disease:
Lean body mass 		G 0.700 GeneticVariation GWASCAT Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locus. 28743860 2017
dbSNP: rs3765350
rs3765350
Entrez Id: 54361
Gene Symbol: WNT4
WNT4
CUI: C0005938
Disease:
Bone Density 		G 0.700 GeneticVariation GWASCAT Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locus. 28743860 2017
dbSNP: rs55938609
rs55938609
Entrez Id: 54361;105376845
Gene Symbol: WNT4;LOC105376845
WNT4;LOC105376845
CUI: C0014175
Disease:
Endometriosis 		0.700 GeneticVariation GWASCAT Genome-wide genetic analyses highlight mitogen-activated protein kinase (MAPK) signaling in the pathogenesis of endometriosis. 28333195 2017
dbSNP: rs3820282
rs3820282
Entrez Id: 54361;105376845
Gene Symbol: WNT4;LOC105376845
WNT4;LOC105376845
CUI: C0677886
Disease:
Epithelial ovarian cancer 		0.700 GeneticVariation GWASCAT Identification of six new susceptibility loci for invasive epithelial ovarian cancer. 25581431 2015