PON1, paraoxonase 1, 5444

N. diseases: 496; N. variants: 29
Disease: Obesity ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs662
rs662
Entrez Id: 5444
Gene Symbol: PON1
PON1
CUI: C0028754
Disease:
Obesity 		0.040 GeneticVariation BEFREE The SNP rs662 in the paraoxonase 1 gene (PON1 Q192R) has been associated with obesity, dyslipidemia and cardiovascular risk. 25500007 2015
dbSNP: rs662
rs662
Entrez Id: 5444
Gene Symbol: PON1
PON1
CUI: C0028754
Disease:
Obesity 		0.040 GeneticVariation BEFREE There were no significant associations between PON1 Q192R genotypes and smoking by genotype interactions and obesity or overweight, while body mass index significantly increased MetS risk. 25037113 2014
dbSNP: rs662
rs662
Entrez Id: 5444
Gene Symbol: PON1
PON1
CUI: C0028754
Disease:
Obesity 		0.040 GeneticVariation BEFREE The allele R of the Q192R polymorphism is associated with an increased risk for development of obesity among Portuguese Caucasian premenopausal women. 21078685 2011
dbSNP: rs662
rs662
Entrez Id: 5444
Gene Symbol: PON1
PON1
CUI: C0028754
Disease:
Obesity 		0.040 GeneticVariation BEFREE We investigated the association between PON1 Q192R polymorphism and the risk of myocardial infarction (MI) and in particular, whether the association can be modified by diabetes mellitus (DM) and obesity. 15654230 2005