POU2F1, POU class 2 homeobox 1, 5451

N. diseases: 115; N. variants: 7
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs552304070
rs552304070
Entrez Id: 5451
Gene Symbol: POU2F1
POU2F1
CUI: C1836230
Disease:
HUMAN IMMUNODEFICIENCY VIRUS TYPE 1, SUSCEPTIBILITY TO 		A 0.700 GeneticVariation GWASCAT Association Between Single-Nucleotide Polymorphisms in HLA Alleles and Human Immunodeficiency Virus Type 1 Viral Load in Demographically Diverse, Antiretroviral Therapy-Naive Participants From the Strategic Timing of AntiRetroviral Treatment Trial. 31219150 2019
dbSNP: rs552304070
rs552304070
Entrez Id: 5451
Gene Symbol: POU2F1
POU2F1
CUI: C1836231
Disease:
HIV-1, RESISTANCE TO 		A 0.700 GeneticVariation GWASCAT Association Between Single-Nucleotide Polymorphisms in HLA Alleles and Human Immunodeficiency Virus Type 1 Viral Load in Demographically Diverse, Antiretroviral Therapy-Naive Participants From the Strategic Timing of AntiRetroviral Treatment Trial. 31219150 2019
dbSNP: rs552304070
rs552304070
Entrez Id: 5451
Gene Symbol: POU2F1
POU2F1
CUI: C1836232
Disease:
ACQUIRED IMMUNODEFICIENCY SYNDROME, PROGRESSION TO 		A 0.700 GeneticVariation GWASCAT Association Between Single-Nucleotide Polymorphisms in HLA Alleles and Human Immunodeficiency Virus Type 1 Viral Load in Demographically Diverse, Antiretroviral Therapy-Naive Participants From the Strategic Timing of AntiRetroviral Treatment Trial. 31219150 2019
dbSNP: rs552304070
rs552304070
Entrez Id: 5451
Gene Symbol: POU2F1
POU2F1
CUI: C0376705
Disease:
Viral Load result 		A 0.700 GeneticVariation GWASCAT Association Between Single-Nucleotide Polymorphisms in HLA Alleles and Human Immunodeficiency Virus Type 1 Viral Load in Demographically Diverse, Antiretroviral Therapy-Naive Participants From the Strategic Timing of AntiRetroviral Treatment Trial. 31219150 2019
dbSNP: rs552304070
rs552304070
Entrez Id: 5451
Gene Symbol: POU2F1
POU2F1
CUI: C1836233
Disease:
AIDS, PROGRESSION TO 		A 0.700 GeneticVariation GWASCAT Association Between Single-Nucleotide Polymorphisms in HLA Alleles and Human Immunodeficiency Virus Type 1 Viral Load in Demographically Diverse, Antiretroviral Therapy-Naive Participants From the Strategic Timing of AntiRetroviral Treatment Trial. 31219150 2019
dbSNP: rs7524019
rs7524019
Entrez Id: 5451
Gene Symbol: POU2F1
POU2F1
CUI: C0428883
Disease:
Diastolic blood pressure 		C 0.700 GeneticVariation GWASCAT Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits. 30224653 2018
dbSNP: rs10918682
rs10918682
Entrez Id: 5451
Gene Symbol: POU2F1
POU2F1
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.020 GeneticVariation BEFREE The rs10918682 in POU2F1 was associated with T2D [P<0.001, OR 3.606 (95% CI 2.165-6.005)]. 24477584 2014
dbSNP: rs3767434
rs3767434
Entrez Id: 5451
Gene Symbol: POU2F1
POU2F1
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.020 GeneticVariation BEFREE Haplotype GAA from rs2146727-10918682-rs3767434 was protective against diabetes (P<0.01) and GGA exhibited the association with T2D (P<0.01). 24477584 2014
dbSNP: rs10918682
rs10918682
Entrez Id: 5451
Gene Symbol: POU2F1
POU2F1
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.020 GeneticVariation BEFREE We found significant associations of rs4657652, rs7532692, rs10918682 and rs3767434 (OR = 1.26-1.59, 0.0003 < P(unadjusted) < 0.035) with Type 2 diabetes in the clinic-based case-control cohorts. 21059098 2010
dbSNP: rs3767434
rs3767434
Entrez Id: 5451
Gene Symbol: POU2F1
POU2F1
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.020 GeneticVariation BEFREE We found significant associations of rs4657652, rs7532692, rs10918682 and rs3767434 (OR = 1.26-1.59, 0.0003 < P(unadjusted) < 0.035) with Type 2 diabetes in the clinic-based case-control cohorts. 21059098 2010
dbSNP: rs2146727
rs2146727
Entrez Id: 5451
Gene Symbol: POU2F1
POU2F1
CUI: C0011847
Disease:
Diabetes 		0.010 GeneticVariation BEFREE Haplotype GAA from rs2146727-10918682-rs3767434 was protective against diabetes (P<0.01) and GGA exhibited the association with T2D (P<0.01). 24477584 2014
dbSNP: rs2146727
rs2146727
Entrez Id: 5451
Gene Symbol: POU2F1
POU2F1
CUI: C0011849
Disease:
Diabetes Mellitus 		0.010 GeneticVariation BEFREE Haplotype GAA from rs2146727-10918682-rs3767434 was protective against diabetes (P<0.01) and GGA exhibited the association with T2D (P<0.01). 24477584 2014
dbSNP: rs2146727
rs2146727
Entrez Id: 5451
Gene Symbol: POU2F1
POU2F1
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.010 GeneticVariation BEFREE Haplotype GAA from rs2146727-10918682-rs3767434 was protective against diabetes (P<0.01) and GGA exhibited the association with T2D (P<0.01). 24477584 2014
dbSNP: rs3767434
rs3767434
Entrez Id: 5451
Gene Symbol: POU2F1
POU2F1
CUI: C0011847
Disease:
Diabetes 		0.010 GeneticVariation BEFREE Haplotype GAA from rs2146727-10918682-rs3767434 was protective against diabetes (P<0.01) and GGA exhibited the association with T2D (P<0.01). 24477584 2014
dbSNP: rs3767434
rs3767434
Entrez Id: 5451
Gene Symbol: POU2F1
POU2F1
CUI: C0011849
Disease:
Diabetes Mellitus 		0.010 GeneticVariation BEFREE Haplotype GAA from rs2146727-10918682-rs3767434 was protective against diabetes (P<0.01) and GGA exhibited the association with T2D (P<0.01). 24477584 2014
dbSNP: rs4657652
rs4657652
Entrez Id: 5451
Gene Symbol: POU2F1
POU2F1
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.010 GeneticVariation BEFREE We found significant associations of rs4657652, rs7532692, rs10918682 and rs3767434 (OR = 1.26-1.59, 0.0003 < P(unadjusted) < 0.035) with Type 2 diabetes in the clinic-based case-control cohorts. 21059098 2010
dbSNP: rs7532692
rs7532692
Entrez Id: 5451
Gene Symbol: POU2F1
POU2F1
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.010 GeneticVariation BEFREE We found significant associations of rs4657652, rs7532692, rs10918682 and rs3767434 (OR = 1.26-1.59, 0.0003 < P(unadjusted) < 0.035) with Type 2 diabetes in the clinic-based case-control cohorts. 21059098 2010