Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2299869
rs2299869
Entrez Id: 5467
Gene Symbol: PPARD
PPARD
CUI: C0392885
Disease:
High density lipoprotein measurement 		0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622 2012
dbSNP: rs2299869
rs2299869
Entrez Id: 5467
Gene Symbol: PPARD
PPARD
CUI: C0428472
Disease:
Serum HDL cholesterol measurement 		0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622 2012
dbSNP: rs2395622
rs2395622
Entrez Id: 5467
Gene Symbol: PPARD
PPARD
CUI: C0871470
Disease:
Systolic Pressure 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs3734254
rs3734254
Entrez Id: 5467
Gene Symbol: PPARD
PPARD
CUI: C0489786
Disease:
Height 		0.700 GeneticVariation GWASDB Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height. 21194676 2011
dbSNP: rs3798343
rs3798343
Entrez Id: 5467
Gene Symbol: PPARD
PPARD
CUI: C0003868
Disease:
Arthritis, Gouty 		0.700 GeneticVariation GWASCAT Gout and type 2 diabetes have a mutual inter-dependent effect on genetic risk factors and higher incidences. 22179738 2012
dbSNP: rs3798343
rs3798343
Entrez Id: 5467
Gene Symbol: PPARD
PPARD
CUI: C0018099
Disease:
Gout 		0.700 GeneticVariation GWASCAT Gout and type 2 diabetes have a mutual inter-dependent effect on genetic risk factors and higher incidences. 22179738 2012
dbSNP: rs9462078
rs9462078
Entrez Id: 5467
Gene Symbol: PPARD
PPARD
CUI: C0489786
Disease:
Height 		0.700 GeneticVariation GWASDB Identification, replication, and fine-mapping of Loci associated with adult height in individuals of african ancestry. 21998595 2011
dbSNP: rs9470003
rs9470003
Entrez Id: 5467
Gene Symbol: PPARD
PPARD
CUI: C0489786
Disease:
Height 		0.700 GeneticVariation GWASDB Identification, replication, and fine-mapping of Loci associated with adult height in individuals of african ancestry. 21998595 2011
dbSNP: rs9470004
rs9470004
Entrez Id: 5467
Gene Symbol: PPARD
PPARD
CUI: C0005890
Disease:
Body Height 		0.700 GeneticVariation GWASCAT Genetic analyses of diverse populations improves discovery for complex traits. 31217584 2019
dbSNP: rs9658113
rs9658113
Entrez Id: 5467
Gene Symbol: PPARD
PPARD
CUI: C0392885
Disease:
High density lipoprotein measurement 		0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622 2012
dbSNP: rs9658113
rs9658113
Entrez Id: 5467
Gene Symbol: PPARD
PPARD
CUI: C0428472
Disease:
Serum HDL cholesterol measurement 		0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622 2012
dbSNP: rs9658131
rs9658131
Entrez Id: 5467
Gene Symbol: PPARD
PPARD
CUI: C0202236
Disease:
Triglycerides measurement 		0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622 2012
dbSNP: rs9658134
rs9658134
Entrez Id: 5467
Gene Symbol: PPARD
PPARD
CUI: C0005890
Disease:
Body Height 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs9658150
rs9658150
Entrez Id: 5467
Gene Symbol: PPARD
PPARD
CUI: C0428474
Disease:
Serum LDL cholesterol measurement 		0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622 2012
dbSNP: rs9658150
rs9658150
Entrez Id: 5467
Gene Symbol: PPARD
PPARD
CUI: C0202236
Disease:
Triglycerides measurement 		0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622 2012
dbSNP: rs9658150
rs9658150
Entrez Id: 5467
Gene Symbol: PPARD
PPARD
CUI: C0202117
Disease:
Low density lipoprotein cholesterol measurement 		0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622 2012
dbSNP: rs2016520
rs2016520
Entrez Id: 5467
Gene Symbol: PPARD
PPARD
CUI: C0028754
Disease:
Obesity 		0.060 GeneticVariation BEFREE C-C haplotype, constructed from rs2016520 and rs9794 alleles, showed a significant protective effect for both abnormal weight and abdominal obesity. 26073637 2016
dbSNP: rs2016520
rs2016520
Entrez Id: 5467
Gene Symbol: PPARD
PPARD
CUI: C0028754
Disease:
Obesity 		0.060 GeneticVariation BEFREE rs2016520 and rs10865170 were associated with lower obesity risk. 23545576 2013
dbSNP: rs2016520
rs2016520
Entrez Id: 5467
Gene Symbol: PPARD
PPARD
CUI: C0028754
Disease:
Obesity 		0.060 GeneticVariation BEFREE Accumulated evidence suggests that the polymorphism rs2016520 in PPARD is associated with lipid metabolism, obesity, metabolic syndrome, and type 2 diabetes mellitus. 28128413 2017
dbSNP: rs2016520
rs2016520
Entrez Id: 5467
Gene Symbol: PPARD
PPARD
CUI: C0028754
Disease:
Obesity 		0.060 GeneticVariation BEFREE After adjustment for gender, age, and smoking status, it was found that the carriers of the C allele (TC + CC) of rs2016520 were associated with a decreased risk of abdominal obesity compared to the carriers of the TT genotype (mean difference = -2.63, 95% CI = -3.61--1.64, P < 0.0001). 23273766 2012
dbSNP: rs2016520
rs2016520
Entrez Id: 5467
Gene Symbol: PPARD
PPARD
CUI: C0028754
Disease:
Obesity 		0.060 GeneticVariation BEFREE Polymorphism of rs2016520 in gene PPARD has been associated with lipid metabolism, obesity, metabolic syndrome and type 2 diabetes mellitus (T2DM). 26915488 2016
dbSNP: rs2016520
rs2016520
Entrez Id: 5467
Gene Symbol: PPARD
PPARD
CUI: C0028754
Disease:
Obesity 		0.060 GeneticVariation BEFREE Previous studies have identified a single-nucleotide polymorphism in the gene encoding peroxisome proliferator-activated receptor-delta (PPARD), rs2016520, that is associated with changes in metabolic disease in some but not all studies, which suggests that PPARD agonists may have therapeutic benefits for the treatment of metabolic disorders, including dyslipidemia, type 2 diabetes, and obesity. 20200337 2010
dbSNP: rs2016520
rs2016520
Entrez Id: 5467
Gene Symbol: PPARD
PPARD
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.040 GeneticVariation BEFREE Previous studies have identified a single-nucleotide polymorphism in the gene encoding peroxisome proliferator-activated receptor-delta (PPARD), rs2016520, that is associated with changes in metabolic disease in some but not all studies, which suggests that PPARD agonists may have therapeutic benefits for the treatment of metabolic disorders, including dyslipidemia, type 2 diabetes, and obesity. 20200337 2010
dbSNP: rs2016520
rs2016520
Entrez Id: 5467
Gene Symbol: PPARD
PPARD
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.040 GeneticVariation BEFREE There was an association between rs2016520 and height in both patients with type 2 diabetes and controls without diabetes (combined P = 5 x 10(-5)). 19383774 2009
dbSNP: rs2016520
rs2016520
Entrez Id: 5467
Gene Symbol: PPARD
PPARD
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.040 GeneticVariation BEFREE Polymorphism of rs2016520 in gene PPARD has been associated with lipid metabolism, obesity, metabolic syndrome and type 2 diabetes mellitus (T2DM). 26915488 2016