PBRM1, polybromo 1, 55193

N. diseases: 105; N. variants: 54
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs864321679
rs864321679
Entrez Id: 55193;440957
Gene Symbol: PBRM1;SMIM4
PBRM1;SMIM4
CUI: C0279702
Disease:
Conventional (Clear Cell) Renal Cell Carcinoma 		C 0.700 CausalMutation CLINVAR
dbSNP: rs2251219
rs2251219
Entrez Id: 55193;440957
Gene Symbol: PBRM1;SMIM4
PBRM1;SMIM4
CUI: C0525045
Disease:
Mood Disorders 		0.810 GeneticVariation GWASCAT We identified SNPs at 3p21.1 associated with major mood disorders (rs2251219, P = 3.63 x 10(-8); odds ratio = 0.87; 95% confidence interval, 0.83-0.92), with supportive evidence for association observed in two out of three independent replication cohorts. 20081856 2010
dbSNP: rs2251219
rs2251219
Entrez Id: 55193;440957
Gene Symbol: PBRM1;SMIM4
PBRM1;SMIM4
CUI: C0525045
Disease:
Mood Disorders 		0.810 GeneticVariation GWASDB We identified SNPs at 3p21.1 associated with major mood disorders (rs2251219, P = 3.63 x 10(-8); odds ratio = 0.87; 95% confidence interval, 0.83-0.92), with supportive evidence for association observed in two out of three independent replication cohorts. 20081856 2010
dbSNP: rs2251219
rs2251219
Entrez Id: 55193;440957
Gene Symbol: PBRM1;SMIM4
PBRM1;SMIM4
CUI: C0525045
Disease:
Mood Disorders 		0.810 GeneticVariation BEFREE We identified SNPs at 3p21.1 associated with major mood disorders (rs2251219, P = 3.63 x 10(-8); odds ratio = 0.87; 95% confidence interval, 0.83-0.92), with supportive evidence for association observed in two out of three independent replication cohorts. 20081856 2010
dbSNP: rs2251219
rs2251219
Entrez Id: 55193;440957
Gene Symbol: PBRM1;SMIM4
PBRM1;SMIM4
CUI: C1269683
Disease:
Major Depressive Disorder 		0.710 GeneticVariation BEFREE Suggestive but notable results were (a) gene-based tests suggesting roles for adenylate cyclase 3 (ADCY3, 2p23.3) and galanin (GAL, 11q13.3); published functional evidence relates both of these to MDD and serotonergic signaling; (b) support for the bipolar disorder risk variant SNP rs1006737 in CACNA1C (P=0.020, odds ratio=1.10); and (c) lack of support for rs2251219, a SNP identified in a meta-analysis of affective disorder studies (P=0.51). 21042317 2012
dbSNP: rs2251219
rs2251219
Entrez Id: 55193;440957
Gene Symbol: PBRM1;SMIM4
PBRM1;SMIM4
CUI: C0005586
Disease:
Bipolar Disorder 		0.720 GeneticVariation GWASDB Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder. 22182935 2013
dbSNP: rs10865974
rs10865974
Entrez Id: 26354;55193
Gene Symbol: GNL3;PBRM1
GNL3;PBRM1
CUI: C0005586
Disease:
Bipolar Disorder 		0.700 GeneticVariation GWASDB Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder. 22182935 2013
dbSNP: rs11714565
rs11714565
Entrez Id: 55193;440957
Gene Symbol: PBRM1;SMIM4
PBRM1;SMIM4
CUI: C0005586
Disease:
Bipolar Disorder 		0.700 GeneticVariation GWASDB Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder. 22182935 2013
dbSNP: rs11720243
rs11720243
Entrez Id: 55193
Gene Symbol: PBRM1
PBRM1
CUI: C0005586
Disease:
Bipolar Disorder 		0.700 GeneticVariation GWASDB Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder. 22182935 2013
dbSNP: rs12487445
rs12487445
Entrez Id: 55193
Gene Symbol: PBRM1
PBRM1
CUI: C0005586
Disease:
Bipolar Disorder 		0.700 GeneticVariation GWASDB Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder. 22182935 2013
dbSNP: rs12487591
rs12487591
Entrez Id: 55193
Gene Symbol: PBRM1
PBRM1
CUI: C0005586
Disease:
Bipolar Disorder 		0.700 GeneticVariation GWASDB Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder. 22182935 2013
dbSNP: rs13064064
rs13064064
Entrez Id: 55193
Gene Symbol: PBRM1
PBRM1
CUI: C0005586
Disease:
Bipolar Disorder 		0.700 GeneticVariation GWASDB Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder. 22182935 2013
dbSNP: rs13068293
rs13068293
Entrez Id: 55193
Gene Symbol: PBRM1
PBRM1
CUI: C0005586
Disease:
Bipolar Disorder 		0.700 GeneticVariation GWASDB Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder. 22182935 2013
dbSNP: rs1561337
rs1561337
Entrez Id: 55193
Gene Symbol: PBRM1
PBRM1
CUI: C0005586
Disease:
Bipolar Disorder 		0.700 GeneticVariation GWASDB Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder. 22182935 2013
dbSNP: rs1866268
rs1866268
Entrez Id: 26354;55193
Gene Symbol: GNL3;PBRM1
GNL3;PBRM1
CUI: C0005586
Disease:
Bipolar Disorder 		0.700 GeneticVariation GWASDB Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder. 22182935 2013
dbSNP: rs1961958
rs1961958
Entrez Id: 55193;440957
Gene Symbol: PBRM1;SMIM4
PBRM1;SMIM4
CUI: C0005586
Disease:
Bipolar Disorder 		0.700 GeneticVariation GWASDB Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder. 22182935 2013
dbSNP: rs2289250
rs2289250
Entrez Id: 55193
Gene Symbol: PBRM1
PBRM1
CUI: C0005586
Disease:
Bipolar Disorder 		0.700 GeneticVariation GWASDB Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder. 22182935 2013
dbSNP: rs2336146
rs2336146
Entrez Id: 55193
Gene Symbol: PBRM1
PBRM1
CUI: C0005586
Disease:
Bipolar Disorder 		0.700 GeneticVariation GWASDB Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder. 22182935 2013
dbSNP: rs2336149
rs2336149
Entrez Id: 55193
Gene Symbol: PBRM1
PBRM1
CUI: C0005586
Disease:
Bipolar Disorder 		0.700 GeneticVariation GWASDB Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder. 22182935 2013
dbSNP: rs2878628
rs2878628
Entrez Id: 55193;440957
Gene Symbol: PBRM1;SMIM4
PBRM1;SMIM4
CUI: C0005586
Disease:
Bipolar Disorder 		0.700 GeneticVariation GWASDB Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder. 22182935 2013
dbSNP: rs3733045
rs3733045
Entrez Id: 55193
Gene Symbol: PBRM1
PBRM1
CUI: C0005586
Disease:
Bipolar Disorder 		0.700 GeneticVariation GWASDB Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder. 22182935 2013
dbSNP: rs3755806
rs3755806
Entrez Id: 55193
Gene Symbol: PBRM1
PBRM1
CUI: C0005586
Disease:
Bipolar Disorder 		0.700 GeneticVariation GWASDB Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder. 22182935 2013
dbSNP: rs3774366
rs3774366
Entrez Id: 55193
Gene Symbol: PBRM1
PBRM1
CUI: C0005586
Disease:
Bipolar Disorder 		0.700 GeneticVariation GWASDB Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder. 22182935 2013
dbSNP: rs3796353
rs3796353
Entrez Id: 55193;440957
Gene Symbol: PBRM1;SMIM4
PBRM1;SMIM4
CUI: C0005586
Disease:
Bipolar Disorder 		0.700 GeneticVariation GWASDB Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder. 22182935 2013
dbSNP: rs6778844
rs6778844
Entrez Id: 55193;440957
Gene Symbol: PBRM1;SMIM4
PBRM1;SMIM4
CUI: C0005586
Disease:
Bipolar Disorder 		0.700 GeneticVariation GWASDB Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder. 22182935 2013