SOX6, SRY-box transcription factor 6, 55553

N. diseases: 105; N. variants: 46
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1455114
rs1455114
Entrez Id: 55553
Gene Symbol: SOX6
SOX6
CUI: C0410702
Disease:
Adolescent idiopathic scoliosis 		0.700 GeneticVariation GWASCAT Genome-wide meta-analysis and replication studies in multiple ethnicities identify novel adolescent idiopathic scoliosis susceptibility loci. 30395268 2018
dbSNP: rs10766309
rs10766309
Entrez Id: 55553
Gene Symbol: SOX6
SOX6
CUI: C0001948
Disease:
Alcohol consumption 		A 0.700 GeneticVariation GWASCAT Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries. 29912962 2018
dbSNP: rs11023906
rs11023906
Entrez Id: 55553
Gene Symbol: SOX6
SOX6
CUI: C0001948
Disease:
Alcohol consumption 		A 0.700 GeneticVariation GWASCAT Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries. 29912962 2018
dbSNP: rs12799126
rs12799126
Entrez Id: 55553
Gene Symbol: SOX6
SOX6
CUI: C0001948
Disease:
Alcohol consumption 		T 0.700 GeneticVariation GWASCAT Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries. 29912962 2018
dbSNP: rs2218001
rs2218001
Entrez Id: 55553
Gene Symbol: SOX6
SOX6
CUI: C0001948
Disease:
Alcohol consumption 		A 0.700 GeneticVariation GWASCAT Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries. 29912962 2018
dbSNP: rs7118275
rs7118275
Entrez Id: 55553
Gene Symbol: SOX6
SOX6
CUI: C0001948
Disease:
Alcohol consumption 		T 0.700 GeneticVariation GWASCAT Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries. 29912962 2018
dbSNP: rs893311
rs893311
Entrez Id: 55553
Gene Symbol: SOX6
SOX6
CUI: C0001948
Disease:
Alcohol consumption 		T 0.700 GeneticVariation GWASCAT Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries. 29912962 2018
dbSNP: rs1455114
rs1455114
Entrez Id: 55553
Gene Symbol: SOX6
SOX6
CUI: C0039585
Disease:
Androgen-Insensitivity Syndrome 		0.010 GeneticVariation BEFREE There was no significant association of rs1455114 with AIS. 30994600 2019
dbSNP: rs16933090
rs16933090
Entrez Id: 55553
Gene Symbol: SOX6
SOX6
CUI: C0003850
Disease:
Arteriosclerosis 		0.010 GeneticVariation BEFREE We presume that the rs16933090 plays a minor role in the development of subclinical atherosclerosis in subjects with T2DM. 26868133 2016
dbSNP: rs16933090
rs16933090
Entrez Id: 55553
Gene Symbol: SOX6
SOX6
CUI: C0004153
Disease:
Atherosclerosis 		0.010 GeneticVariation BEFREE We presume that the rs16933090 plays a minor role in the development of subclinical atherosclerosis in subjects with T2DM. 26868133 2016
dbSNP: rs1156725
rs1156725
Entrez Id: 55553
Gene Symbol: SOX6
SOX6
CUI: C0005823
Disease:
Blood Pressure 		0.700 GeneticVariation GWASDB Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. 21909110 2011
dbSNP: rs1401454
rs1401454
Entrez Id: 55553
Gene Symbol: SOX6
SOX6
CUI: C0005823
Disease:
Blood Pressure 		T 0.700 GeneticVariation GWASDB Genome-wide association analysis of blood-pressure traits in African-ancestry individuals reveals common associated genes in African and non-African populations. 23972371 2013
dbSNP: rs1595373
rs1595373
Entrez Id: 55553
Gene Symbol: SOX6
SOX6
CUI: C0005823
Disease:
Blood Pressure 		0.700 GeneticVariation GWASDB Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. 21909110 2011
dbSNP: rs2014408
rs2014408
Entrez Id: 55553
Gene Symbol: SOX6
SOX6
CUI: C0005823
Disease:
Blood Pressure 		0.700 GeneticVariation GWASDB Blood pressure loci identified with a gene-centric array. 22100073 2011
dbSNP: rs1455115
rs1455115
Entrez Id: 55553
Gene Symbol: SOX6
SOX6
CUI: C0005890
Disease:
Body Height 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs12800049
rs12800049
Entrez Id: 55553
Gene Symbol: SOX6
SOX6
CUI: C0005938
Disease:
Bone Density 		T 0.700 GeneticVariation GWASCAT Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects. 29304378 2018
dbSNP: rs12801635
rs12801635
Entrez Id: 55553
Gene Symbol: SOX6
SOX6
CUI: C0005938
Disease:
Bone Density 		T 0.700 GeneticVariation GWASCAT Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects. 29304378 2018
dbSNP: rs16932777
rs16932777
Entrez Id: 55553
Gene Symbol: SOX6
SOX6
CUI: C0005938
Disease:
Bone Density 		C 0.700 GeneticVariation GWASCAT Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects. 29304378 2018
dbSNP: rs35199438
rs35199438
Entrez Id: 55553
Gene Symbol: SOX6
SOX6
CUI: C0005938
Disease:
Bone Density 		T 0.700 GeneticVariation GWASCAT Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects. 29304378 2018
dbSNP: rs3809095
rs3809095
Entrez Id: 10944;55553
Gene Symbol: C11orf58;SOX6
C11orf58;SOX6
CUI: C0005938
Disease:
Bone Density 		A 0.700 GeneticVariation GWASCAT Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects. 29304378 2018
dbSNP: rs7131442
rs7131442
Entrez Id: 55553
Gene Symbol: SOX6
SOX6
CUI: C0005938
Disease:
Bone Density 		A 0.700 GeneticVariation GWASCAT Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects. 29304378 2018
dbSNP: rs10832571
rs10832571
Entrez Id: 55553
Gene Symbol: SOX6
SOX6
CUI: C0007222
Disease:
Cardiovascular Diseases 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs16933090
rs16933090
Entrez Id: 55553
Gene Symbol: SOX6
SOX6
CUI: C0577631
Disease:
Carotid Atherosclerosis 		0.010 GeneticVariation BEFREE In our study, we demonstrated the effect of the rs16933090 on coronary calcium score obtained at CCTA, whereas we did not demonstrate an important effect of the rs16933090 on either subclinical markers of carotid atherosclerosis or the presence of more than 50% stenotic lesions in coronary arteries in Caucasians with T2DM. 26868133 2016
dbSNP: rs16933090
rs16933090
Entrez Id: 55553
Gene Symbol: SOX6
SOX6
CUI: C0010054
Disease:
Coronary Arteriosclerosis 		0.010 GeneticVariation BEFREE The second aim of the study was to demonstrate an association between the rs16933090 and subclinical markers of coronary artery disease in the same subset of patients with T2DM. 26868133 2016
dbSNP: rs34156428
rs34156428
Entrez Id: 55553
Gene Symbol: SOX6
SOX6
CUI: C1956346
Disease:
Coronary Artery Disease 		A 0.700 GeneticVariation GWASCAT Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease. 29212778 2018