|
rs12122803
|
C1orf112
|
Venous Thromboembolism
|
|
0.700 |
GeneticVariation |
GWASCAT |
Genomic and transcriptomic association studies identify 16 novel susceptibility loci for venous thromboembolism.
|
31420334 |
2019 |
|
rs185120584
|
C1orf112
|
Venous Thromboembolism
|
|
0.700 |
GeneticVariation |
GWASCAT |
Genomic and transcriptomic association studies identify 16 novel susceptibility loci for venous thromboembolism.
|
31420334 |
2019 |
|
rs6427212
|
C1orf112
|
Hypertensive disease
|
|
0.010 |
GeneticVariation |
BEFREE |
In single-marker analyses, each copy of the minor alleles of correlated SELE markers rs4656704, rs6427212, and rs5368 were associated with increased risk of developing hypertension (P for trend = 1.48 × 10(-4), 6.69 × 10(-5), and 7.64 × 10(-5), respectively).
|
25424718 |
2015 |
|
rs16862512
|
C1orf112;LOC107985745
|
Cardiac troponin T measurement
|
C |
0.700 |
GeneticVariation |
GWASCAT |
Cardiac Troponin T and Troponin I in the General Population.
|
31014085 |
2019 |
|
rs7531806
|
C1orf112;LOC107985745
|
Acne Vulgaris
|
A |
0.700 |
GeneticVariation |
GWASCAT |
Two new susceptibility loci 1q24.2 and 11p11.2 confer risk to severe acne.
|
24399259 |
2014 |
|
rs10489177
|
C1orf112;METTL18
|
Ischemic stroke
|
|
0.010 |
GeneticVariation |
BEFREE |
Collectively, our study identified two novel loci (rs17118 and rs10489177) which were associated with an increased risk for IS in Chinese Han populations.
|
24122314 |
2014 |
|
rs10489177
|
C1orf112;METTL18
|
Diabetes Mellitus
|
|
0.010 |
GeneticVariation |
BEFREE |
The rs10489177 GG genotype was associated with significantly increased risk for IS in individuals without hypertension (OR = 2.78, 95 % CI = 1.59-4.86) and in individuals without diabetes (OR = 1.93, 95 % CI = 1.27-2.94).
|
24122314 |
2014 |
|
rs10489177
|
C1orf112;METTL18
|
Diabetes
|
|
0.010 |
GeneticVariation |
BEFREE |
The rs10489177 GG genotype was associated with significantly increased risk for IS in individuals without hypertension (OR = 2.78, 95 % CI = 1.59-4.86) and in individuals without diabetes (OR = 1.93, 95 % CI = 1.27-2.94).
|
24122314 |
2014 |
|
rs10489177
|
C1orf112;METTL18
|
Hypertensive disease
|
|
0.010 |
GeneticVariation |
BEFREE |
The rs10489177 GG genotype was associated with significantly increased risk for IS in individuals without hypertension (OR = 2.78, 95 % CI = 1.59-4.86) and in individuals without diabetes (OR = 1.93, 95 % CI = 1.27-2.94).
|
24122314 |
2014 |
|
rs4265482
|
SELE;C1orf112
|
Blood Protein Measurement
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Co-regulatory networks of human serum proteins link genetics to disease.
|
30072576 |
2018 |
|
rs1458766475
|
SELE;C1orf112
|
Coronary heart disease
|
|
0.090 |
GeneticVariation |
BEFREE |
The interaction of classical risk factors for CAD with S128R polymorphism in our study population showed that the significant determinants of coronary artery disease were presence of diabetes, hypertension, smoking habit, elevated serum triglycerides and low HDL.
|
19942746 |
2009 |
|
rs1458766475
|
SELE;C1orf112
|
Coronary heart disease
|
|
0.090 |
GeneticVariation |
BEFREE |
E-selectin S128R polymorphism and severe coronary artery disease in Arabs.
|
16756647 |
2006 |
|
rs1458766475
|
SELE;C1orf112
|
Coronary heart disease
|
|
0.090 |
GeneticVariation |
BEFREE |
All P-selectin polymorphisms as well as a common E-selectin polymorphism, Ser128Arg which has been reported as being associated with an increased risk of premature coronary heart disease (CHD), and is in tight linkage disequilibrium with several P-selectin polymorphisms, were investigated in 647 patients with MI and 758 control subjects from four regions of France and Northern Ireland (the ECTIM study).
|
9668170 |
1998 |
|
rs1458766475
|
SELE;C1orf112
|
Coronary heart disease
|
|
0.090 |
GeneticVariation |
BEFREE |
The interactive role of type 2 diabetes mellitus and E-selectin S128R mutation on susceptibility to coronary heart disease.
|
17578587 |
2007 |
|
rs1458766475
|
SELE;C1orf112
|
Coronary heart disease
|
|
0.090 |
GeneticVariation |
BEFREE |
We found a correlation between the M235T molecular variant of AGT and the S128R variant of E-selectin to early severe CHD.
|
9020385 |
1997 |
|
rs1458766475
|
SELE;C1orf112
|
Coronary heart disease
|
|
0.090 |
GeneticVariation |
BEFREE |
An association between the Ser128 Arg polymorphism and coronary heart disease (CHD) has been previously demonstrated in a white population.
|
15871853 |
2005 |
|
rs1458766475
|
SELE;C1orf112
|
Coronary heart disease
|
|
0.090 |
GeneticVariation |
BEFREE |
Association between the Ser128Arg variant of the E-selectin and risk of coronary artery disease in the central China.
|
16061120 |
2005 |
|
rs1458766475
|
SELE;C1orf112
|
Coronary heart disease
|
|
0.090 |
GeneticVariation |
BEFREE |
In subjects suffering from diabetes mellitus type 2 the E-selectin S128R polymorphism is not associated with coronary artery disease nor with an increased risk for myocardial infarction.
|
15013273 |
2003 |
|
rs1458766475
|
SELE;C1orf112
|
Coronary heart disease
|
|
0.090 |
GeneticVariation |
BEFREE |
The results of our meta-analysis suggest that SELE genetic polymorphisms might be strongly correlated with an increased risk of CHD (allele model: OR 2.08, 95% CI 1.67-2.58, P<0.001; dominant model: OR 2.12, 95% CI 1.68-2.68, P<0.001; respectively), especially the SELE 554L/F, 98G/T and 128S/R polymorphisms.
|
24458828 |
2014 |
|
rs5361
|
SELE;C1orf112
|
Coronary heart disease
|
|
0.090 |
GeneticVariation |
BEFREE |
The results of our meta-analysis suggest that SELE genetic polymorphisms might be strongly correlated with an increased risk of CHD (allele model: OR 2.08, 95% CI 1.67-2.58, P<0.001; dominant model: OR 2.12, 95% CI 1.68-2.68, P<0.001; respectively), especially the SELE 554L/F, 98G/T and 128S/R polymorphisms.
|
24458828 |
2014 |
|
rs5361
|
SELE;C1orf112
|
Coronary heart disease
|
|
0.090 |
GeneticVariation |
BEFREE |
Association between the Ser128Arg variant of the E-selectin and risk of coronary artery disease in the central China.
|
16061120 |
2005 |
|
rs5361
|
SELE;C1orf112
|
Coronary heart disease
|
|
0.090 |
GeneticVariation |
BEFREE |
We found a correlation between the M235T molecular variant of AGT and the S128R variant of E-selectin to early severe CHD.
|
9020385 |
1997 |
|
rs5361
|
SELE;C1orf112
|
Coronary heart disease
|
|
0.090 |
GeneticVariation |
BEFREE |
In subjects suffering from diabetes mellitus type 2 the E-selectin S128R polymorphism is not associated with coronary artery disease nor with an increased risk for myocardial infarction.
|
15013273 |
2003 |
|
rs5361
|
SELE;C1orf112
|
Coronary heart disease
|
|
0.090 |
GeneticVariation |
BEFREE |
The interactive role of type 2 diabetes mellitus and E-selectin S128R mutation on susceptibility to coronary heart disease.
|
17578587 |
2007 |
|
rs5361
|
SELE;C1orf112
|
Coronary heart disease
|
|
0.090 |
GeneticVariation |
BEFREE |
An association between the Ser128 Arg polymorphism and coronary heart disease (CHD) has been previously demonstrated in a white population.
|
15871853 |
2005 |