Disease: Coronary heart disease ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1458766475
rs1458766475
Entrez Id: 6401;55732
Gene Symbol: SELE;C1orf112
SELE;C1orf112
CUI: C0010068
Disease:
Coronary heart disease 		0.090 GeneticVariation BEFREE The results of our meta-analysis suggest that SELE genetic polymorphisms might be strongly correlated with an increased risk of CHD (allele model: OR 2.08, 95% CI 1.67-2.58, P<0.001; dominant model: OR 2.12, 95% CI 1.68-2.68, P<0.001; respectively), especially the SELE 554L/F, 98G/T and 128S/R polymorphisms. 24458828 2014
dbSNP: rs1458766475
rs1458766475
Entrez Id: 6401;55732
Gene Symbol: SELE;C1orf112
SELE;C1orf112
CUI: C0010068
Disease:
Coronary heart disease 		0.090 GeneticVariation BEFREE The interaction of classical risk factors for CAD with S128R polymorphism in our study population showed that the significant determinants of coronary artery disease were presence of diabetes, hypertension, smoking habit, elevated serum triglycerides and low HDL. 19942746 2009
dbSNP: rs1458766475
rs1458766475
Entrez Id: 6401;55732
Gene Symbol: SELE;C1orf112
SELE;C1orf112
CUI: C0010068
Disease:
Coronary heart disease 		0.090 GeneticVariation BEFREE The interactive role of type 2 diabetes mellitus and E-selectin S128R mutation on susceptibility to coronary heart disease. 17578587 2007
dbSNP: rs1458766475
rs1458766475
Entrez Id: 6401;55732
Gene Symbol: SELE;C1orf112
SELE;C1orf112
CUI: C0010068
Disease:
Coronary heart disease 		0.090 GeneticVariation BEFREE E-selectin S128R polymorphism and severe coronary artery disease in Arabs. 16756647 2006
dbSNP: rs1458766475
rs1458766475
Entrez Id: 6401;55732
Gene Symbol: SELE;C1orf112
SELE;C1orf112
CUI: C0010068
Disease:
Coronary heart disease 		0.090 GeneticVariation BEFREE An association between the Ser128 Arg polymorphism and coronary heart disease (CHD) has been previously demonstrated in a white population. 15871853 2005
dbSNP: rs1458766475
rs1458766475
Entrez Id: 6401;55732
Gene Symbol: SELE;C1orf112
SELE;C1orf112
CUI: C0010068
Disease:
Coronary heart disease 		0.090 GeneticVariation BEFREE Association between the Ser128Arg variant of the E-selectin and risk of coronary artery disease in the central China. 16061120 2005
dbSNP: rs1458766475
rs1458766475
Entrez Id: 6401;55732
Gene Symbol: SELE;C1orf112
SELE;C1orf112
CUI: C0010068
Disease:
Coronary heart disease 		0.090 GeneticVariation BEFREE In subjects suffering from diabetes mellitus type 2 the E-selectin S128R polymorphism is not associated with coronary artery disease nor with an increased risk for myocardial infarction. 15013273 2003
dbSNP: rs1458766475
rs1458766475
Entrez Id: 6401;55732
Gene Symbol: SELE;C1orf112
SELE;C1orf112
CUI: C0010068
Disease:
Coronary heart disease 		0.090 GeneticVariation BEFREE All P-selectin polymorphisms as well as a common E-selectin polymorphism, Ser128Arg which has been reported as being associated with an increased risk of premature coronary heart disease (CHD), and is in tight linkage disequilibrium with several P-selectin polymorphisms, were investigated in 647 patients with MI and 758 control subjects from four regions of France and Northern Ireland (the ECTIM study). 9668170 1998
dbSNP: rs1458766475
rs1458766475
Entrez Id: 6401;55732
Gene Symbol: SELE;C1orf112
SELE;C1orf112
CUI: C0010068
Disease:
Coronary heart disease 		0.090 GeneticVariation BEFREE We found a correlation between the M235T molecular variant of AGT and the S128R variant of E-selectin to early severe CHD. 9020385 1997