PRKCE, protein kinase C epsilon, 5581

N. diseases: 112; N. variants: 51
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs3738894
rs3738894
Entrez Id: 5581
Gene Symbol: PRKCE
PRKCE
CUI: C0279626
Disease:
Squamous cell carcinoma of esophagus 		0.010 GeneticVariation BEFREE A case-control study including 494 ESCC patients and 494 controls was carried out to investigate the genetic susceptibility of 4 microRNA-binding site SNPs (rs712 in the binding site of KRAS to let-7, rs8904 in the binding site of NFBIA to mir-507, rs3738894 in the binding site of protein kinase C epsilon to mir-218, rs701848 in the binding site of phosphatase and tensin to mir-1304) as well as the interactions of gene-environment in the development of ESCC. 31269493 2020
dbSNP: rs3738894
rs3738894
Entrez Id: 5581
Gene Symbol: PRKCE
PRKCE
CUI: C0014859
Disease:
Esophageal Neoplasms 		0.010 GeneticVariation BEFREE The gene-Environment interaction between rs3738894 and smoking history was associated with the risk of esophageal cancer. 31269493 2020
dbSNP: rs3738894
rs3738894
Entrez Id: 5581
Gene Symbol: PRKCE
PRKCE
CUI: C0152018
Disease:
Esophageal carcinoma 		0.010 GeneticVariation BEFREE The gene-Environment interaction between rs3738894 and smoking history was associated with the risk of esophageal cancer. 31269493 2020
dbSNP: rs3738894
rs3738894
Entrez Id: 5581
Gene Symbol: PRKCE
PRKCE
CUI: C0546837
Disease:
Malignant neoplasm of esophagus 		0.010 GeneticVariation BEFREE The gene-Environment interaction between rs3738894 and smoking history was associated with the risk of esophageal cancer. 31269493 2020
dbSNP: rs10168349
rs10168349
Entrez Id: 5581
Gene Symbol: PRKCE
PRKCE
CUI: C0018935
Disease:
Hematocrit procedure 		G 0.800 GeneticVariation GWASCAT Genome-wide association study of hematological and biochemical traits in a Japanese population. 20139978 2010
dbSNP: rs10168349
rs10168349
Entrez Id: 5581
Gene Symbol: PRKCE
PRKCE
CUI: C0018935
Disease:
Hematocrit procedure 		0.800 GeneticVariation GWASCAT Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. 29403010 2018
dbSNP: rs10168349
rs10168349
Entrez Id: 5581
Gene Symbol: PRKCE
PRKCE
CUI: C0018935
Disease:
Hematocrit procedure 		C 0.800 GeneticVariation GWASCAT Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium. 19862010 2009
dbSNP: rs10495928
rs10495928
Entrez Id: 5581
Gene Symbol: PRKCE
PRKCE
CUI: C0518015
Disease:
Hemoglobin measurement 		G 0.800 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
dbSNP: rs10495928
rs10495928
Entrez Id: 5581
Gene Symbol: PRKCE
PRKCE
CUI: C0518015
Disease:
Hemoglobin measurement 		G 0.800 GeneticVariation GWASCAT Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium. 19862010 2009
dbSNP: rs4953318
rs4953318
Entrez Id: 5581
Gene Symbol: PRKCE
PRKCE
CUI: C0014772
Disease:
Red Blood Cell Count measurement 		0.800 GeneticVariation GWASCAT Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis. 28017375 2017
dbSNP: rs10168349
rs10168349
Entrez Id: 5581
Gene Symbol: PRKCE
PRKCE
CUI: C0014772
Disease:
Red Blood Cell Count measurement 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs10168349
rs10168349
Entrez Id: 5581
Gene Symbol: PRKCE
PRKCE
CUI: C0014772
Disease:
Red Blood Cell Count measurement 		0.700 GeneticVariation GWASCAT Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. 29403010 2018
dbSNP: rs10168349
rs10168349
Entrez Id: 5581
Gene Symbol: PRKCE
PRKCE
CUI: C0014772
Disease:
Red Blood Cell Count measurement 		C 0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
dbSNP: rs10168349
rs10168349
Entrez Id: 5581
Gene Symbol: PRKCE
PRKCE
CUI: C0518015
Disease:
Hemoglobin measurement 		0.700 GeneticVariation GWASCAT Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. 29403010 2018
dbSNP: rs10192064
rs10192064
Entrez Id: 5581
Gene Symbol: PRKCE
PRKCE
CUI: C0428419
Disease:
Triiodothyronine measurement 		C 0.700 GeneticVariation GWASCAT Genome-wide association meta-analysis for total thyroid hormone levels in Croatian population. 30824882 2019
dbSNP: rs10495928
rs10495928
Entrez Id: 5581
Gene Symbol: PRKCE
PRKCE
CUI: C0018935
Disease:
Hematocrit procedure 		G 0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
dbSNP: rs10495928
rs10495928
Entrez Id: 5581
Gene Symbol: PRKCE
PRKCE
CUI: C0014772
Disease:
Red Blood Cell Count measurement 		G 0.700 GeneticVariation GWASCAT Genome-wide association study of hematological and biochemical traits in a Japanese population. 20139978 2010
dbSNP: rs10865207
rs10865207
Entrez Id: 5581
Gene Symbol: PRKCE
PRKCE
CUI: C1305855
Disease:
Body mass index 		A 0.700 GeneticVariation GWASCAT Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits. 28552196 2017
dbSNP: rs114948639
rs114948639
Entrez Id: 5581
Gene Symbol: PRKCE
PRKCE
CUI: C0018935
Disease:
Hematocrit procedure 		T 0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
dbSNP: rs114948639
rs114948639
Entrez Id: 5581
Gene Symbol: PRKCE
PRKCE
CUI: C0518015
Disease:
Hemoglobin measurement 		T 0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
dbSNP: rs114948639
rs114948639
Entrez Id: 5581
Gene Symbol: PRKCE
PRKCE
CUI: C0014772
Disease:
Red Blood Cell Count measurement 		T 0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
dbSNP: rs12623399
rs12623399
Entrez Id: 5581
Gene Symbol: PRKCE
PRKCE
CUI: C0014772
Disease:
Red Blood Cell Count measurement 		C 0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
dbSNP: rs12712955
rs12712955
Entrez Id: 5581
Gene Symbol: PRKCE
PRKCE
CUI: C0202117
Disease:
Low density lipoprotein cholesterol measurement 		A 0.700 GeneticVariation GWASCAT Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program. 30275531 2018
dbSNP: rs12712955
rs12712955
Entrez Id: 5581
Gene Symbol: PRKCE
PRKCE
CUI: C1445957
Disease:
Serum total cholesterol measurement 		A 0.700 GeneticVariation GWASCAT Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program. 30275531 2018
dbSNP: rs12999972
rs12999972
Entrez Id: 5581
Gene Symbol: PRKCE
PRKCE
CUI: C0005890
Disease:
Body Height 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019