PRKCI, protein kinase C iota, 5584

N. diseases: 78; N. variants: 3
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs114153063
rs114153063
Entrez Id: 5584
Gene Symbol: PRKCI
PRKCI
CUI: C0200638
Disease:
Eosinophil count procedure 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs71277158
rs71277158
Entrez Id: 5584
Gene Symbol: PRKCI
PRKCI
CUI: C0600139
Disease:
Prostate carcinoma 		T 0.700 GeneticVariation GWASCAT Two susceptibility loci identified for prostate cancer aggressiveness. 25939597 2015
dbSNP: rs546950
rs546950
Entrez Id: 5584
Gene Symbol: PRKCI
PRKCI
CUI: C0600139
Disease:
Prostate carcinoma 		0.020 GeneticVariation BEFREE In conclusion, the results revealed that PRKCI rs546950 variant decreased the risk of PCa in an Iranian population. 26475383 2015
dbSNP: rs546950
rs546950
Entrez Id: 5584
Gene Symbol: PRKCI
PRKCI
CUI: C0376358
Disease:
Malignant neoplasm of prostate 		0.020 GeneticVariation BEFREE In conclusion, the results revealed that PRKCI rs546950 variant decreased the risk of PCa in an Iranian population. 26475383 2015
dbSNP: rs546950
rs546950
Entrez Id: 5584
Gene Symbol: PRKCI
PRKCI
CUI: C0600139
Disease:
Prostate carcinoma 		0.020 GeneticVariation BEFREE In the joint analysis of first and second phase two SNPs of the PRKCI gene showed an association with risk of prostate cancer (OR(allele) = 0.85, 95% CI 0.78-0.94, p = 1.3 x 10⁻³ for rs546950 and OR(allele) = 0.84, 95% CI 0.76-0.93, p = 5.6 x 10⁻⁴ for rs4955720). 21373201 2011
dbSNP: rs546950
rs546950
Entrez Id: 5584
Gene Symbol: PRKCI
PRKCI
CUI: C0376358
Disease:
Malignant neoplasm of prostate 		0.020 GeneticVariation BEFREE In the joint analysis of first and second phase two SNPs of the PRKCI gene showed an association with risk of prostate cancer (OR(allele) = 0.85, 95% CI 0.78-0.94, p = 1.3 x 10⁻³ for rs546950 and OR(allele) = 0.84, 95% CI 0.76-0.93, p = 5.6 x 10⁻⁴ for rs4955720). 21373201 2011