MAPK1, mitogen-activated protein kinase 1, 5594

N. diseases: 1059; N. variants: 13
Disease: Squamous cell carcinoma of the head and neck ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1057519911
rs1057519911
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
CUI: C1168401
Disease:
Squamous cell carcinoma of the head and neck 		T 0.710 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
dbSNP: rs1057519911
rs1057519911
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
CUI: C1168401
Disease:
Squamous cell carcinoma of the head and neck 		0.710 GeneticVariation BEFREE The HNSCC cells with MAPK1 E322K exhibited enhanced EGFR phosphorylation and erlotinib sensitivity compared with wild-type MAPK1 cells. 26181029 2015