MAPK7, mitogen-activated protein kinase 7, 5598

N. diseases: 127; N. variants: 6
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2233083
rs2233083
Entrez Id: 4239;5598
Gene Symbol: MFAP4;MAPK7
MFAP4;MAPK7
CUI: C0002395
Disease:
Alzheimer's Disease 		0.700 GeneticVariation GWASCAT Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities. 30636644 2019
dbSNP: rs147296805
rs147296805
Entrez Id: 5598
Gene Symbol: MAPK7
MAPK7
CUI: C2700406
Disease:
SCOLIOSIS, IDIOPATHIC, SUSCEPTIBILITY TO, 1 (finding) 		A 0.700 CausalMutation CLINVAR Rare coding variants in MAPK7 predispose to adolescent idiopathic scoliosis. 28714182 2017
dbSNP: rs1555613564
rs1555613564
Entrez Id: 5598
Gene Symbol: MAPK7
MAPK7
CUI: C2700406
Disease:
SCOLIOSIS, IDIOPATHIC, SUSCEPTIBILITY TO, 1 (finding) 		T 0.700 CausalMutation CLINVAR Rare coding variants in MAPK7 predispose to adolescent idiopathic scoliosis. 28714182 2017
dbSNP: rs758163506
rs758163506
Entrez Id: 5598
Gene Symbol: MAPK7
MAPK7
CUI: C2700406
Disease:
SCOLIOSIS, IDIOPATHIC, SUSCEPTIBILITY TO, 1 (finding) 		T 0.700 CausalMutation CLINVAR Rare coding variants in MAPK7 predispose to adolescent idiopathic scoliosis. 28714182 2017
dbSNP: rs2233074
rs2233074
Entrez Id: 5598
Gene Symbol: MAPK7
MAPK7
CUI: C1445957
Disease:
Serum total cholesterol measurement 		0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622 2012
dbSNP: rs3866958
rs3866958
Entrez Id: 5598;27077
Gene Symbol: MAPK7;B9D1
MAPK7;B9D1
CUI: C1306460
Disease:
Primary malignant neoplasm of lung 		0.010 GeneticVariation BEFREE Our data indicated that the functional polymorphism rs3866958G>T in ERK5 was associated with an increased lung cancer risk in smokers by virtue of the positive interaction with smoking on promoting the ERK5 expression, which might be a valuable indicator for predicting lung cancer risk in smokers. 23804708 2013
dbSNP: rs3866958
rs3866958
Entrez Id: 5598;27077
Gene Symbol: MAPK7;B9D1
MAPK7;B9D1
CUI: C0684249
Disease:
Carcinoma of lung 		0.010 GeneticVariation BEFREE Our data indicated that the functional polymorphism rs3866958G>T in ERK5 was associated with an increased lung cancer risk in smokers by virtue of the positive interaction with smoking on promoting the ERK5 expression, which might be a valuable indicator for predicting lung cancer risk in smokers. 23804708 2013
dbSNP: rs3866958
rs3866958
Entrez Id: 5598;27077
Gene Symbol: MAPK7;B9D1
MAPK7;B9D1
CUI: C0242379
Disease:
Malignant neoplasm of lung 		0.010 GeneticVariation BEFREE Our data indicated that the functional polymorphism rs3866958G>T in ERK5 was associated with an increased lung cancer risk in smokers by virtue of the positive interaction with smoking on promoting the ERK5 expression, which might be a valuable indicator for predicting lung cancer risk in smokers. 23804708 2013