PRL, prolactin, 5617

N. diseases: 506; N. variants: 3
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1341239
rs1341239
Entrez Id: 5617;401237
Gene Symbol: PRL;CASC15
PRL;CASC15
CUI: C0003873
Disease:
Rheumatoid Arthritis 		0.020 GeneticVariation BEFREE PRL -1149T allele (rs1341239) is associated with decreased risk of rheumatoid arthritis in population from southern Mexico: analysis of mRNA expression and PRL serum levels. 30911943 2019
dbSNP: rs1341239
rs1341239
Entrez Id: 5617;401237
Gene Symbol: PRL;CASC15
PRL;CASC15
CUI: C0003873
Disease:
Rheumatoid Arthritis 		0.020 GeneticVariation BEFREE The aim of this study was to determine the role of the PRL -1149 G/T polymorphism (rs1341239) in rheumatoid arthritis (RA) susceptibility. 19404952 2009
dbSNP: rs1341239
rs1341239
Entrez Id: 5617;401237
Gene Symbol: PRL;CASC15
PRL;CASC15
CUI: C0026618
Disease:
Dental Fluorosis, Acquired 		0.010 GeneticVariation BEFREE Prolactin rs1341239 T allele may have protective role against the brick tea type skeletal fluorosis. 28152004 2017
dbSNP: rs1341239
rs1341239
Entrez Id: 5617;401237
Gene Symbol: PRL;CASC15
PRL;CASC15
CUI: C0020514
Disease:
Hyperprolactinemia 		0.010 GeneticVariation BEFREE This study revealed a significant association between the polymorphic variant rs1341239 and the development of hyperprolactinemia in patients with schizophrenia. 27776952 2017
dbSNP: rs1341239
rs1341239
Entrez Id: 5617;401237
Gene Symbol: PRL;CASC15
PRL;CASC15
CUI: C0036341
Disease:
Schizophrenia 		0.010 GeneticVariation BEFREE This study revealed a significant association between the polymorphic variant rs1341239 and the development of hyperprolactinemia in patients with schizophrenia. 27776952 2017
dbSNP: rs1341239
rs1341239
Entrez Id: 5617;401237
Gene Symbol: PRL;CASC15
PRL;CASC15
CUI: C0024141
Disease:
Lupus Erythematosus, Systemic 		0.010 GeneticVariation BEFREE This preliminary study examined the relevance of a -1149G/T functional single-nucleotide polymorphism (SNP) (rs1341239) in the promoter of the extrapituitary prolactin gene in a cohort of African American and European American women with lupus. 26583155 2015
dbSNP: rs1341239
rs1341239
Entrez Id: 5617;401237
Gene Symbol: PRL;CASC15
PRL;CASC15
CUI: C0409974
Disease:
Lupus Erythematosus 		0.010 GeneticVariation BEFREE This preliminary study examined the relevance of a -1149G/T functional single-nucleotide polymorphism (SNP) (rs1341239) in the promoter of the extrapituitary prolactin gene in a cohort of African American and European American women with lupus. 26583155 2015
dbSNP: rs1341239
rs1341239
Entrez Id: 5617;401237
Gene Symbol: PRL;CASC15
PRL;CASC15
CUI: C0024138
Disease:
Lupus Erythematosus, Discoid 		0.010 GeneticVariation BEFREE This preliminary study examined the relevance of a -1149G/T functional single-nucleotide polymorphism (SNP) (rs1341239) in the promoter of the extrapituitary prolactin gene in a cohort of African American and European American women with lupus. 26583155 2015
dbSNP: rs1341239
rs1341239
Entrez Id: 5617;401237
Gene Symbol: PRL;CASC15
PRL;CASC15
CUI: C0024131
Disease:
Lupus Vulgaris 		0.010 GeneticVariation BEFREE This preliminary study examined the relevance of a -1149G/T functional single-nucleotide polymorphism (SNP) (rs1341239) in the promoter of the extrapituitary prolactin gene in a cohort of African American and European American women with lupus. 26583155 2015
dbSNP: rs3756824
rs3756824
Entrez Id: 5617;401237
Gene Symbol: PRL;CASC15
PRL;CASC15
CUI: C0678222
Disease:
Breast Carcinoma 		0.010 GeneticVariation BEFREE The PRL SNP rs3756824 was significantly associated with breast cancer metastasis (P < 0.05). 21125332 2011
dbSNP: rs3756824
rs3756824
Entrez Id: 5617;401237
Gene Symbol: PRL;CASC15
PRL;CASC15
CUI: C0006142
Disease:
Malignant neoplasm of breast 		0.010 GeneticVariation BEFREE The PRL SNP rs3756824 was significantly associated with breast cancer metastasis (P < 0.05). 21125332 2011
dbSNP: rs3756824
rs3756824
Entrez Id: 5617;401237
Gene Symbol: PRL;CASC15
PRL;CASC15
CUI: C0027627
Disease:
Neoplasm Metastasis 		0.010 GeneticVariation BEFREE The PRL SNP rs3756824 was significantly associated with breast cancer metastasis (P < 0.05). 21125332 2011
dbSNP: rs768767532
rs768767532
Entrez Id: 5617;401237
Gene Symbol: PRL;CASC15
PRL;CASC15
CUI: C0004509
Disease:
Azoospermia 		0.010 GeneticVariation BEFREE The frequency of double Trp8Arg and Ile15Thr heterozygotes was similar between the fertile (14.5%, n = 200) and infertile (12.6%, n = 95) groups, with the exception of one homozygous mutation (Arg8 and Thr15) from patient with azoospermia. 12620433 2003