PRSS1, serine protease 1, 5644

N. diseases: 117; N. variants: 33
Disease: Acute pancreatitis ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs10273639
rs10273639
Entrez Id: 5644
Gene Symbol: PRSS1
PRSS1
CUI: C0001339
Disease:
Acute pancreatitis 		0.030 GeneticVariation BEFREE Our findings suggested that rs7057398, rs12688220 and rs10273639 polymorphisms could be used to identify individuals at an elevated susceptibility to acute pancreatitis in Caucasians. 31163246 2020
dbSNP: rs10273639
rs10273639
Entrez Id: 5644
Gene Symbol: PRSS1
PRSS1
CUI: C0001339
Disease:
Acute pancreatitis 		0.030 GeneticVariation BEFREE Meta-analyses of all AP patients depicted significant (p-value < 0.05) associations for rs10273639 (odds ratio (OR) 0.88, 95% confidence interval (CI) 0.81-0.97, p-value 0.01), rs7057398 (OR 1.27, 95% CI 1.07-1.5, p-value 0.005), and rs12688220 (OR 1.32, 95% CI 1.12-1.56, p-value 0.001). 29884332 2018
dbSNP: rs10273639
rs10273639
Entrez Id: 5644
Gene Symbol: PRSS1
PRSS1
CUI: C0001339
Disease:
Acute pancreatitis 		0.030 GeneticVariation BEFREE We confirmed a robust association of polymorphism rs10273639 at PRSS1-PRSS2 with AP in the Russian population. 27846138 2017